Chapter 83 Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation Jennifer A. McArthur, Barbara Bambach, Christine Duncan, Julie-An Talano, Robert T. Tamburro, Jr. Pearls • Patients undergoing allogeneic hematopoietic…
Chapter 106 Toxidromes and Their Treatment Ashley N. Webb, Prashant Joshi Pearls • When given for a benzodiazepine overdose, flumazenil may precipitate acute withdrawal in the patient who habitually uses…
Chapter 90 The Innate Immune System Rachel S. Agbeko, Mark J. Peters Pearls • Innate immunity provides the front-line “ready-made” response to pathogen invasion. • These same pathways are activated…
Chapter 124 Malignant Hyperthermia Barbara W. Brandom, Mihaela Visoiu Pearls • Malignant hyperthermia (MH) is a muscle disorder first recognized as a complication of general anesthesia with the potent inhalational…
Chapter 122 Neuromuscular Blocking Agents Joseph D. Tobias Pearls • As neuromuscular blocking agents (NMBAs) result in blockade of skeletal muscle function, these agents cause cessation of ventilatory function, mandating…
Chapter 72 Pediatric Renal Replacement Therapy in the Intensive Care Unit Jordan M. Symons, Stuart L. Goldstein Pearls • Patients receiving renal replacement therapy require careful monitoring of fluid and…
Chapter 71 Glomerulotubular Dysfunction and Acute Kidney Injury Surender Rajasekaran, Norma J. Maxvold, Timothy E. Bunchman Pearls • Acute kidney injury (AKI) has replaced the term acute kidney failure. There…
Chapter 114 Thoracic Injuries in Children Mauricio A. Escobar, Jr., Michael G. Caty Pearls • Thoracic injuries in children are uncommon but result in significant morbidity and mortality, mainly from…
Chapter 4 Research in Pediatric Critical Care Randall C. Wetzel, Carol E. Nicholson “A fool is a man who never tried an experiment in his life.” Erasmus Darwin, 1792 Pearls…
Chapter 121 Anesthesia Principles and Operating Room Anesthesia Regimens Joseph D. Tobias Intraoperative anesthetic can be provided by one of five techniques, which include local anesthesia (sometimes referred to as…
