Cardiovascular Physiology: Integrative Function

Apr 15, 2019 by in ANESTHESIA Comments Off on Cardiovascular Physiology: Integrative Function

Abstract A thorough understanding of cardiovascular physiology is a cornerstone of patient management in the perioperative period. The primary role of the cardiovascular system is to provide sufficient blood flow…

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Anticoagulant and Antiplatelet Therapy

Apr 15, 2019 by in ANESTHESIA Comments Off on Anticoagulant and Antiplatelet Therapy

Chapter Outline Normal Platelet Function and Hemostasis Mechanisms of Thrombin and Fibrin Generation Indirect Inhibitors of Thrombin Generation Historical Considerations Heparins Low-Molecular-Weight Heparin Pentasaccharide Vitamin K Antagonists Direct Thrombin Inhibitors…

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Intravascular Volume Replacement Therapy

Apr 15, 2019 by in ANESTHESIA Comments Off on Intravascular Volume Replacement Therapy

Abstract This chapter describes conventional concepts about body fluid spaces. It carefully describes physiological principles about fluid shifting in the body and responses to fluid challenges. It further describes different…

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Electrolytes and Diuretics

Apr 15, 2019 by in ANESTHESIA Comments Off on Electrolytes and Diuretics

Abstract This chapter deals with electrolytes and diuretics. It thoroughly goes through pertinent facts about electrolytes such as sodium, potassium, calcium, phosphate, and magnesium. Particular attention is paid to hypo-…

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Transfusion and Coagulation Therapy

Apr 15, 2019 by in ANESTHESIA Comments Off on Transfusion and Coagulation Therapy

Chapter Outline Hemoglobin and Volume Replacement Therapies Historical Aspects of Transfusion Packed Red Blood Cells Clinical Uses Side Effects Erythropoietin Side Effects Blood Substitutes Albumin Synthetic Colloids Hemostatic Interventions and…

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Pharmacology of Postoperative Nausea and Vomiting

Apr 15, 2019 by in ANESTHESIA Comments Off on Pharmacology of Postoperative Nausea and Vomiting

Abstract Postoperative nausea and vomiting (PONV) are common problems following surgery. This chapter is designed to educate the readers on the spectrum of antiemetic therapy available, and to which populations…

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Renal Physiology

Apr 15, 2019 by in ANESTHESIA Comments Off on Renal Physiology

Abstract The main functions of the kidney are (1) regulation of salt and water balance, (2) toxin and metabolite elimination, (3) electrolyte homeostasis, (4) acid–base balance, and (5) hormone production….

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Pulmonary Pharmacology

Apr 15, 2019 by in ANESTHESIA Comments Off on Pulmonary Pharmacology

Abstract Pulmonary pharmacology is focused primarily on medications that effect the conducting airways of the lung responsible for gas exchange at the alveoli. The maintenance of patent airways occurs naturally…

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Blood and Coagulation

Apr 15, 2019 by in ANESTHESIA Comments Off on Blood and Coagulation

Abstract Hemostasis is a critical homeostatic mechanism of survival that involves vascular, cellular, and plasma components that interact to stop bleeding. Vascular effects include vasoconstriction, expression of procoagulant factors such…

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