Chapter 22 Assessment of Cardiovascular Function Melvin C. Almodovar, Thomas J. Kulik, John R. Charpie Pearls • Cardiovascular assessment and monitoring in the pediatric intensive care unit requires careful integration…
Chapter 96 Infectious Syndromes in the Pediatric Intensive Care Unit Sonny Dhanani, Peter N. Cox Pearls • Because of the rapid progression of septicemia from meningococcus and variability of markers…
Chapter 100 Molecular Foundations of Cellular Injury Necrosis, Apoptosis, and Autophagy Jared T. Muenzer, Craig M. Coopersmith Pearls • As an “accidental” form of death, necrosis is an uncontrolled process….
Chapter 101 Endotheliopathy Yves Ouellette, Jan A. Hazelzet Pearls • Because of their location, endothelial cells have the ability to interact with blood components, such as flow, soluble factors, and…
Chapter 73 Hypertension in the Pediatric Intensive Care Unit Ronald C. Sanders, Jr., Arno Zaritsky, Karen McNiece-Redwine Pearls • Systemic hypertension, an often underappreciated condition that is increasing at an…
Chapter 118 Adverse Drug Reactions and Drug-drug Interactions Wade W. Benton, Adam W. Brothers, Christa C. Jefferis Kirk, Gretchen A. Linggi Irby, Christopher M. Rubino Pearls • Although adverse drug…
Chapter 98 Autoimmune Diseases Diagnosis, Treatment, and Life-Threatening Complications Jonna D. Clark, Helen M. Emery Pearls • Approximately 1 child in 250 has a rheumatologic disease. • Children may present…
Chapter 102 Neuroendocrine–Immune Mediator Coordination and Disarray in Critical Illness Kate Felmet, Joseph A. Carcillo Pearls • Activation of the hypothalamic-pituitary-adrenal axis is normal during stress. Lack of activation in…
Chapter 55 Pediatric Neurologic Assessment and Monitoring Mark S. Wainwright Pearls • The examiner should focus both on localization of a neurologic deficit and identifying mechanism(s) of injury (or potential…
Chapter 76 Inborn Errors of Metabolism Laurie Smith, Cary O. Harding Pearls • Unexpected and unexplained clinical deterioration in a previously healthy infant or child is an important clue to…
