The Human Factor
Resilience is built, not born, and there is no single strategy that reliably manufactures resilient performance in all circumstances. Optimizing team performance in dynamic environments involves the complex interplay of…
Damage Control: Advances in Trauma Resuscitation
Amal Mattu, MD, Consulting Editor When I began emergency medicine training, trauma care was considered exciting and “sexy” to my colleagues and me. There was excitement with every case, and…
Damage Control: Advances in Trauma Resuscitation
EMERGENCY MEDICINE CLINICS OF NORTH AMERICA www.emed.theclinics.com Consulting Editor AMAL MATTU February 2018 • Volume 36 • Number 1
The response of the microcirculation to mechanical support of the heart in critical illness
Critical illness associated with cardiac pump failure results in reduced tissue perfusion in all organs and occurs in various conditions such as sepsis, cardiogenic shock, and heart failure. Mechanical circulatory…
Hemodynamic coherence in critically ill pediatric patients
Differences in physiology and pathophysiology make the treatment of developing, critically ill children particularly challenging as compared to that of adults. Significant differences in the cardiovascular system of neonates and…
Red blood cell transfusion and its effect on microvascular dysfunction in shock states
Among critically ill patients, red blood cell (RBC) transfusion is often prescribed for anemia in the absence of active or recent bleeding. The failure of RBC transfusion to improve physiological…
Effects of vasodilators on haemodynamic coherence
Vasodilators are a potential therapeutic option for patients with persisting microcirculatory disorders despite adequate cardiac output and mean arterial pressure due to conventional haemodynamic stabilization. Venous vasodilation may decrease post-capillary…
Effect of non-adrenergic vasopressors on macro- and microvascular coupling in distributive shock
The present review initially describes the rationale for the use of non-adrenergic vasopressors in the treatment of distributive shock and then provides an overview of the individual vasopressin-receptor agonists, namely…
Haemodynamic coherence in perioperative setting
Over the last decade, there has been an increased interest in the use of goal-directed therapy (GDT) in patients undergoing high-risk surgery, and various haemodynamic monitoring tools have been developed…
Haemodynamic coherence in haemorrhagic shock
In case of haemorrhage, a combination of low volume fluid resuscitation and permissive hypotension is used to avoid the adverse effects of early aggressive fluid resuscitation. During this phase, occult microvascular hypoperfusion…
