TABLE 140.2 Commonly Used Drugs that Affect Thyroid Function THYROTOXICOSIS Clinical Presentation In the ICU, patients with thyrotoxicosis may have an atypical presentation, with tachyarrhythmias or central nervous system disturbance…
PATHOPHYSIOLOGY MODS usually occurs in patients who exhibit signs of a generalized inflammatory response (systemic inflammatory response syndrome [SIRS]; Table 52.2) (1). Although SIRS is often the result of infection…
Preeclampsia is defined by the maternal manifestations of hypertension and proteinuria occurring in the second half of pregnancy. The presentation and diagnostic features of preeclampsia are reviewed in Tables 78.2…
FIGURE 14.1 Named branches of the tracheobronchial tree, viewed from the front. (From Nunn JF. Applied Respiratory Physiology. 3rd ed. London: Butterworths; 1987, with permission.) The primary lobular terminal respiratory…
The pH, defined by Sorenson, is the negative log of the concentration of H+. Therefore, in neutral solution, the pH is 7. This is a very small concentration of [H+],…
CLINICAL EXAMINATION The neurologic coma examination, admittedly limited, is still able to offer several localizing clues. The examination includes an assessment of mental status as described earlier, brainstem reflex testing,…
TREATMENT Transfusion Decision-Making Transfusion based on sound physiologic principles and an understanding of relative risks and benefits should give maximal benefit to the patient, with efficient use of a valuable…
The most common inciting event in cardiogenic shock is an acute MI. Historically, once 40% of the myocardium has been irreversibly damaged, cardiogenic shock may result. From a mechanical perspective,…
FIGURE 131.1 Diagram of the collateral pathways for the mesenteric vessels. The celiac axis and superior mesenteric arteries communicate through the superior and inferior pancreaticoduodenal arteries, respectively. The superior and…
MECHANISMS OF CRITICAL ILLNESS–ASSOCIATED DYSREGULATION OF THE ENDOCRINE SYSTEM The Stressors Critically ill patients are unexpectedly faced with a life-threatening situation and a hostile environment (the intensive care unit). Physical…
