12 – Effects on Brain Function

Aug 31, 2020 by in ANESTHESIA Comments Off on 12 – Effects on Brain Function

Abstract Surgery and anaesthesia alter the function of the brain and its control mechanisms. In the operating room, we daily observe the effects of anaesthetic agents during induction and recovery…

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9 – Personalized Sedation and Analgesia

Aug 31, 2020 by in ANESTHESIA Comments Off on 9 – Personalized Sedation and Analgesia

Abstract The practice of medicine often requires procedures that cause pain and anxiety. With the advent of modern anaesthesia these procedures have become commonplace and tolerable. Procedures with the greatest…

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4 – Covariate Analysis in Clinical Anaesthesia

Aug 31, 2020 by in ANESTHESIA Comments Off on 4 – Covariate Analysis in Clinical Anaesthesia

Abstract The goal of pharmacological treatment is a desired response, known as the target effect (e.g. bispectral index of 50). An understanding of the concentration–response relationship (i.e. pharmacodynamics (PD)) can…

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5 – Signal Analysis and Response Measurement

Aug 31, 2020 by in ANESTHESIA Comments Off on 5 – Signal Analysis and Response Measurement

Abstract Monitoring during anaesthesia is based on the measurement of physiological signals that are recorded during surgical or other procedures requiring anaesthetic drug administration. The methods used to process these…

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