Intervention Indications Cautions Side effects Protocol Notes Supranormal elevation of oxygen delivery Critically ill patients at increased risk of death Patients not responding to initial challenge have a worse prognosis…
1st author/year N Durationof study Participants Therapeutic intervention Control intervention Follow-up time Conclusion HACA/2002 [5] 275 65 m Unconscious OHCA patients, cardiac cause of arrest (initial rhythm VF or non-perfusing…
Inclusion criteria 1. Published in peer-reviewed journal 2. Multicenter randomized design 3. Dealt with a nonsurgical intervention (drug/technique/strategy) 4. Involving adult critically ill patients 5. Showing a statistically significant reduction…
Technique Indications Contraindications Side effects Protocol Note High-frequency oscillatory ventilation (HFOV) Acute respiratory distress syndrome with hypoxemia refractory to conventional protective ventilation Recent lung surgery, lung disease characterized by airway…
Drug Indications Contraindications Side effects Dose Note Glutamine (alanyl-glutamine and glycine-glutamine) Critically ill patients (intensive care unit patients, burns, surgical patients) Bone marrow transplant Weight loss in patients with AIDS…
Fig. 13.1 Schematic diagram showing the scientific rationale and potential role of β2-agonists in ARDS (Adopted from: Bassford et al. [13]. Permission to reproduce granted under BioMed Central’s general terms)…
Always available without temperature limitations Long shelf life Effective oxygen-carrying capacity Effective volume expander Absent scavenging effect on nitric oxide No side effects No infectious carrier No crossmatching necessity Cost-effective…
Drug Indications Cautions Side effects Dose Notes Growth hormone Growth hormone deficiency Prolonged intensive care unit stay Diabetes mellitus Chronic renal failure Steroids Critically ill Appears safe Water retention In…
RCTs Mortality with HES Use of RRT with HES RR 95 % CI RR 95 % CI CRYSTMASa 1.23 0.76–2.01 1.83 0.89–3.89 6Sb 1.17 1.01–1.36 1.35 1.01–1.80 CHESTc 1.06 0.96–1.18…
Intervention Indications Cautions Side effects Protocol Notes Intensive insulin therapy (or tight glycemic control) Critically ill patients with stress-induced hyperglycemia (sepsis, stroke, traumatic brain injury, myocardial infarction, trauma, burns, cardiothoracic…
