Noninvasive Ventilation
First author Year N° centers NIV application Setting Mask Patients in NIV group Patients in control group Mortality NIV Mortality control Brochard [5] 1995 5 Hypercapnic ICU Face 43 42…
Daily Interruption of Sedatives to Improve Outcomes in Critically Ill Patients
Fig. 7.1 Survival benefit of daily interruption of sedatives paired with spontaneous breathing trials. In the Awakening and Breathing Controlled Trial, patients in the intervention group were managed with daily…
Prone Positioning to Reduce Mortality in Acute Respiratory Distress Syndrome
Fig. 4.1 The greater lung expansion in ventral regions, due to shape matching between the lung and thorax, counteracts the gravitational forces when they act on those ventral regions, as…
Lung-Protective Ventilation and Mortality in Acute Respiratory Distress Syndrome
Fig. 3.1 Calculation of predicted body weight (PBW). cm centimeters, in inches (Modified from Silversides et al. [2] Copyright © 2013 BioMed Central Ltd) Finally, Villar and colleagues [11] enrolled…
Decision Making in the Democracy-based Medicine Era: The Consensus Conference Process
Increasing survival Increasing mortality Albumin in hepatorenal syndrome [9] Supranormal elevation of systemic oxygen delivery [25] Daily interruption of sedatives [10] Diaspirin cross-linked hemoglobin [26] Mild hypothermia [11] Growth hormone…
Albumin Use in Liver Cirrhosis
Proven applications Possible applications Strong evidence Lack of strong evidence but physiological rationale Large-volume paracentesis Recurrent ascites (as a long-term treatment) Spontaneous bacterial peritonitis (SBP) with ascites Non-SBP-related sepsis and…
Tranexamic Acid in Trauma Patients
Meta-analyses Size Mortality Blood transfusion Myocardial infarction Stroke Pulmonary embolism RCT pts RR 95 % CI RR 95 % CI RR 95 % CI RR 95 % CI RR 95…
