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Vasopressors and Inotropes in Sepsis

Dec 13, 2017 by in Uncategorized Comments Off on Vasopressors and Inotropes in Sepsis

Vasopressor and inotropes are beneficial in shock states. Norepinephrine is considered the first-line vasopressor for patients with sepsis-associated hypotension. Dobutamine is considered the first-line inotrope in sepsis, and should be…

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Fluid Resuscitation in Severe Sepsis

Dec 13, 2017 by in Uncategorized Comments Off on Fluid Resuscitation in Severe Sepsis

Since its original description in 1832, fluid resuscitation has become the cornerstone of early and aggressive treatment of severe sepsis and septic shock. However, questions remain about optimal fluid composition,…

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Source Identification and Source Control

Dec 13, 2017 by in Uncategorized Comments Off on Source Identification and Source Control

Identifying sources of infection and establishing source control is an essential component of the workup and treatment of sepsis. Investigation with history, physical examination, laboratory tests, and imaging can in…

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Appropriate Antibiotic Therapy

Dec 13, 2017 by in Uncategorized Comments Off on Appropriate Antibiotic Therapy

Prescribing antibiotics is an essential component of initial therapy in sepsis. Early antibiotics are an important component of therapy, but speed of administration should not overshadow the patient-specific characteristics that…

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The New Usual Care

Dec 13, 2017 by in Uncategorized Comments Off on The New Usual Care

Recent literature continues to refine which components of the early goal-directed therapy (EGDT) algorithm are necessary. Given it utilizes central venous pressure, continuous central venous oxygen saturation, routine blood transfusions,…

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Defining and Diagnosing Sepsis

Dec 13, 2017 by in Uncategorized Comments Off on Defining and Diagnosing Sepsis

Sepsis is a heterogeneous clinical syndrome that encompasses infections of many different types and severity. Not surprisingly, it has confounded most attempts to apply a single definition, which has also…

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Preparing for International Travel and Global Medical Care

Dec 13, 2017 by in Uncategorized Comments Off on Preparing for International Travel and Global Medical Care

Thorough pretravel preparation and medical consultation can mitigate avoidable health and safety risks. A comprehensive pretravel medical consultation should include an individualized risk assessment, immunization review, and discussion of arthropod…

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