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Addressing Host Factors: Overview of Dependence and Addiction
(1) Northern Anesthesia & Pain Medicine, LLC, Eagle River, Alaska, USA (2) WWAMI Program, University of Washington School of Medicine, Anchorage, Alaska, USA KeywordsOpioidHostDependenceAddictionPseudoaddictionCravingChoiceCompulsionConditioningOperantIncentive sensitizationRewardHedonic toneOpponent processAllostasisLocus of controlBiologic…
Best Practices Education, Part I: Pain Physiology, Psychology, and Alternatives to Opioids
(1) Northern Anesthesia & Pain Medicine, LLC, Eagle River, Alaska, USA (2) WWAMI Program, University of Washington School of Medicine, Anchorage, Alaska, USA KeywordsOpioidVectorTransmissionBest practicesPainEvidence basedCartesianNociceptionTransductionAδDorsal hornSensitizationWindupModulationPerceptionGate theoryInterneuronNeuromatrixBiopsychosocialPreventionMultimodalSpiritual A…
Opioid Dependence Risk Factors and Risk Assessment
(1) Northern Anesthesia & Pain Medicine, LLC, Eagle River, Alaska, USA (2) WWAMI Program, University of Washington School of Medicine, Anchorage, Alaska, USA KeywordsOpioidHostMisuseDependenceAddictionOpioid use disorderExposure reductionRisk factorNESARCSubstance use…
Attenuating the Agent: Reducing Opioid “Virulence”
(1) Northern Anesthesia & Pain Medicine, LLC, Eagle River, Alaska, USA (2) WWAMI Program, University of Washington School of Medicine, Anchorage, Alaska, USA KeywordsAgentPathogenicAntibiotic resistanceVirulenceAntivirulenceOpioidAttenuationMesolimbicNucleus accumbensVentral tegmental areaExtended-releaseLong-actingControlled-releaseSustained-releaseTimed-releaseOxyContinRisk evaluation…
