Basic Principles of Clinical Pharmacology
Basic Principles of Clinical Pharmacology Dhanesh K. Gupta Thomas K. Henthorn Key Points Most drugs must pass through cell membranes to reach their sites of action. Consequently, drugs tend to…
ANESTHESIA
Experimental Design and Statistics
Experimental Design and Statistics Nathan Leon Pace Key Points Statistics and mathematics are the language of scientific medicine. Good research planning includes a clear biologic hypothesis, the specification of outcome…
Genomic Basis of Perioperative Medicine
Genomic Basis of Perioperative Medicine Kevin Friede Joseph P. Mathew Mihai V. Podgoreanu Key Points Despite the tremendous success of recent genome-wide association studies (GWAS) in identifying genetic variants associated…
Mechanisms of Anesthesia and Consciousness
Mechanisms of Anesthesia and Consciousness C. Michael Crowder Ben Julian Palanca Alex S. Evers Key Points The components of the anesthetic state include unconsciousness, amnesia, analgesia, immobility, and attenuation of…
Occupational Health
Occupational Health Jonathan D. Katz Robert S. Holzman Key Points Exposure to waste anesthetic gases can be reduced to levels below those recommended by the National Institute for Occupational Safety…
Anesthetic Risk, Quality Improvement, and Liability
Anesthetic Risk, Quality Improvement, and Liability Karen L. Posner Saint Adeogba Karen B. Domino Key Points Anesthetic mortality has decreased, but accidental deaths and disabling complications still occur. Risk management…
Scope of Practice
Scope of Practice John H. Eichhorn Jay S. Grider Key Points Anesthesia trainees, and many postgraduates also, tend to lack sufficient knowledge (with sometimes unfortunate results) about modes of practice…
The History of Anesthesia
The History of Anesthesia Adam K. Jacob Sandra L. Kopp Douglas R. Bacon Hugh M. Smith Key Points Anesthesiology is a young specialty historically, especially when compared with surgery or…
FOR OBSTETRIC AND GYNECOLOGIC SURGERY
ANESTHESIA FOR LABOR AND DELIVERY • Nonpharmacologic analgesia choices: Hypnotherapy, hydrotherapy, and transcutaneous electrical nerve stimulation (TENS) • Pharmacologic analgesia: Inhalation analgesia, parenteral opioid analgesia (fentanyl, nalbuphine), pudendal block, paracervical…
ELECTROLYTES, & TRANSFUSION THERAPY
(LR, NS, & hetastarch → shown to ↑ neutrophil activation; blood, 7.5% hypertonic saline, & albumin did not have this effect) Figure 9-1. Assessment of volume status. Colloid osmotic pressure (COP)…
