ANESTHESIA

Clinical measurement

Jan 18, 2017 by in ANESTHESIA Comments Off on Clinical measurement

Figure 45.1 The measurement system as a ‘black box’ The measurement system in turn consists of component ‘black boxes’ representing: A transducer – a detecting element which converts the quantity…

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Renal physiology

Jan 18, 2017 by in ANESTHESIA Comments Off on Renal physiology

Figure 16.1 (a) Anatomy and (b) vasculature of the kidney Blood supply of the kidneys The kidneys receive 20% of cardiac output via the renal arteries. The renal artery to…

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Pharmacodynamics

Jan 18, 2017 by in ANESTHESIA Comments Off on Pharmacodynamics

which is graphically demonstrated in Figures 26.4, 26.5 and 26.6. In this chapter the steps in the derivation of this and other equations are shown in boxes. In this chapter…

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Physiology of the circulation

Jan 18, 2017 by in ANESTHESIA Comments Off on Physiology of the circulation

Figure 15.1 Adult circulation system Structure and function Blood vessel walls are basically structured in three layers. The adventitia is the outer layer and is made up of connective tissue…

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Pharmacokinetics

Jan 18, 2017 by in ANESTHESIA Comments Off on Pharmacokinetics

Figure 27.1 Overview of pharmacokinetic processes Drug administration Drugs are administered by many different routes. The aim of drug administration is to achieve therapeutic levels of the drug at its…

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Physiology of the nervous system

Jan 18, 2017 by in ANESTHESIA Comments Off on Physiology of the nervous system

Figure 18.2 A typical neurone Figure 18.3 Classification of mammalian neurones Fibre type Function Fibre diameter (mm) Conduction speed (ms–1) Aα Proprioception, somatic motor 12–20 70–120 Aβ Touch, pressure 2–12…

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Cellular physiology

Jan 18, 2017 by in ANESTHESIA Comments Off on Cellular physiology

↑ glycogen synthesis↑ protein synthesis↑ triacylglycerol synthesis↑ fatty acid synthesis↓ glycogenolysis↓ ketone formation↓ breakdown of triglyceridesGlucagonAlpha cells in the islets of Langerhans↑ glycogenolysis↑ ketone formation↑ gluconeogenesisAdrenalineAdrenal medulla↑ glycogenolysis↑ gluconeogenesis↑ lipolysisCortisolAdrenal…

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Physiology of pain

Jan 18, 2017 by in ANESTHESIA Comments Off on Physiology of pain

Figure 19.1 The nociceptive pathway Dimensions of the pain experience Pain has a protective function and may or may not be associated with tissue damage. Pain should not be equated…

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Muscle physiology

Jan 18, 2017 by in ANESTHESIA Comments Off on Muscle physiology

Figure 13.2 Macroscopic structure of skeletal muscle Microscopic structure Each muscle cell runs the length of the muscle belly and is polynucleate. The vast majority of muscle cells are innervated…

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Regional anaesthesia

Jan 18, 2017 by in ANESTHESIA Comments Off on Regional anaesthesia

Figure 7.3 Lidocaine toxicity Cardiovascular and central nervous system toxicity depend on the mass of drug reaching the systemic circulation. The transfer of drug (by diffusion) from the circulation to…

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