CHAPTER 11 Local Anesthetics

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Show moreShow less Introduction Local anesthetics (LAs) form the subset of drugs that provide analgesia and anesthesia by reversible conduction blockade of autonomic, sensory, and motor nerve impulses. The earliest…

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CHAPTER 10 Muscle Relaxants (AS4.1)

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Show moreShow less Introduction Discovery and use of muscle relaxants in anesthesia practice dates back to 1942, when Griffith and Johnson used d-tubocurarine to provide muscle relaxation during surgery. Since…

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CHAPTER 9 Intravenous Anesthetic Agents (AS4.1)

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Show moreShow less Introduction Intravenous (IV) anesthetic agents are the most common drugs used in day-to-day anesthesia practice. It encompasses agents like sedative-hypnotics, anxiolytics, opioids, and muscle relaxants. The combination…

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CHAPTER 8 Inhalational Anesthetics (AS4.1)

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Show moreShow less Introduction Any chemical agent with general anesthetic properties and the ability to be delivered via inhalation is labeled as an “inhalational anesthetic agent.” Characteristics of an ideal…

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CHAPTER 7 Glimpse of General Anesthesia

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Show moreShow less Introduction General anesthesia is a drug-induced, reversible condition, including specific behavioral and physiological components, with concomitant stability of the autonomic, cardiovascular, respiratory, and thermoregulatory system. It can…

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CHAPTER 6 Monitoring in Anesthesia

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Show moreShow less Introduction Monitoring in anesthesia had been in place long before the introduction of clinical anesthesia. The importance of respiratory pattern was known since antiquity. Work by William…

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CHAPTER 5 Blood Transfusion (AS9.4)

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Show moreShow less Historical Background Blood transfusion, often a life-saving strategy, historically dates back to the Egyptian and Roman era. Egyptians took a blood bath as a recuperative measure, while…

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CHAPTER 3 Preoperative Checkup

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Show moreShow less Introduction (AS3.1) Anesthetizing a patient without a preoperative check is like traveling in an airplane without a pilot. Preoperative assessment is the cornerstone of perioperative care by…

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CHAPTER 4 Fluids (AS9.3)

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Show moreShow less Introduction Fluid therapy is an integral component of perioperative care by anesthesia providers. Administration of fluid helps to prevent dehydration, maintains effective circulatory volume, and ensures adequate…

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CHAPTER 2 Historical Milestones in Anesthesia

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Show moreShow less Introduction On October 16, 1846 (considered as the era of the beginning of anesthesia), William TG Morton gave the first successful public demonstration of anesthesia using ether…

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