Anaphylaxis
Risk • Lifetime prevalence of anaphylaxis is 0.05% to 2%, most common triggers being food, stings, and iatrogenic causes. • Occurs in approximately 1 in 10,000 to 1 in 20,000…
Amyotrophic Lateral Sclerosis
Risk • Estimated incidence of 1-3:100,000. • Mean age of onset is in the 60s, but ALS can occur as early as the 20s. • Disease duration is approximately 3…
Anemia, Aplastic
Risk • Incidence in USA: 2000 new cases/y. • Per million up to age 9. • Southeast Asia and South Africa have 10-20 times higher incidence. • Within USA, related…
Anemia, Megaloblastic
Risk • Prevalence: Estimates ranging from 1.7-3.6%. • Most common cause is vitamin deficiency: 65% vitamin B12; 12% combined folate/vitamin B12; 6% folate. • Pernicious anemia is less common: 1…
Anemia, Hemolytic
Risk • Autoimmune disorders (SLE, RA, scleroderma, cold agglutinin disease). • Lymphoproliferative disorders (CLL, NHL). • Prosthetic heart valves (ball-and-cage, and bileaflet valves). Usually subclinical, but can be severe in…
Alpha 1-Antitrypsin Deficiency
Risk • One of the most common inherited disorders (1 in 2500 in case of European ancestry; uncommon in Asians) • Less than 10% of individuals with AAT deficiency are…
Alcohol Abuse
Risk • Incidence in USA: 10% of Americans, incl physicians, will abuse alcohol at some point in their lives. • 1:5 surgical pts has some form of alcohol use disorder….
Amniotic Fluid Embolism
Risk • Risk factors include: advanced maternal age (>35 y); cesarean delivery; placenta previa; meconium; intrauterine fetal demise; placental abruption; meconium staining of the amniotic fluid; chorioamnionitis; and macrosomia. •…
Amyloidosis
Risk • Incidence in USA: 1:100,000 • Race with highest prevalence: Unknown Perioperative Risks • Increased risk of periop renal failure, cardiomyopathy (arrhythmias and ventricular dysfunction), bleeding from coagulopathy •…
