Peripheral Neuropathies
INTRODUCTION Print Section Listen Painful polyneuropathy (PN) is a debilitating neurologic problem and frequently a challenging therapeutic management issue. Difficulties in managing patients are too often the result of poor…
Medical Management of Cancer Pain
OVERVIEW Print Section Listen Cancer pain is usually caused directly by neoplastic injury to pain-sensitive structures. For this reason, primary antineoplastic therapy, including radiation, chemotherapy, and palliative surgery, should be…
Pain in the Elderly
INTRODUCTION Print Section Listen It is well known that we are an aging society with 20% of the population reaching 65 years or older by the year 2030.1 Older Americans…
Sickle-Cell Disease
INTRODUCTION Print Section Listen Sickle-cell disease (SCD) is the most prevalent single-gene disorder, affecting about 100,000 Americans. Sickle-cell disease is a debilitating condition associated with chronic anemia, stroke, splenic and…
Fibromyalgia
INTRODUCTION Print Section Listen Understanding of fibromyalgia syndrome (FMS) has evolved over the past 20 years. Once thought to be related to muscular pain and inflammation, it is now more…
Pain Management in End of Life: Palliative Care
INTRODUCTION Print Section Listen The basic principles of the diagnosis and management of pain syndromes are similar across all clinical settings. Details of the application of these principles, however, can…
Cancer Pain and Palliative Care in Children
INTRODUCTION Print Section Listen The prognosis of cancer in children has improved dramatically over the past 40 years. Unlike many adult cancers, pediatric malignancies are often responsive to initial aggressive…
Cancer Pain Syndromes
OVERVIEW Print Section Listen Pain is a complex symptom experienced by many cancer patients. It affects most aspects of life, and controlling it well can make a great difference in…
Preemptive Analgesia
INTRODUCTION Print Section Listen The understanding of postoperative pain has evolved greatly during the past half century. Many laboratory investigations have established that peripheral tissue injury during surgery can trigger…
Central Neuropathic Pain Following Spinal Cord Injury
INTRODUCTION Print Section Listen The development of debilitating central neuropathic pain (CNP), defined as pain caused by a lesion or dysfunction of the central nervous system (CNS),1,2 can occur after…
