Introduction More than 400,000 people have cardiac arrests in the United States each year, and approximately half of these occur in the hospital. Resuscitation attempts are unsuccessful in the majority…
Introduction Alpha-2 receptor agonists have many desirable effects such as minimum alveolar concentration (MAC) reduction, analgesia, anxiolysis, sedation, and sympatholysis. Adding to this list the possibility of perioperative myocardial protection…
Introduction More than 40 years ago during the Vietnam War, ketamine, a nonbarbiturate phencyclidine derivative, was considered an ideal “battlefield anesthetic” because it does not alter hemodynamics and has sedative,…
Introduction No anesthetic agent has been administered more often than nitrous oxide. Since its first demonstration in 1845, nitrous oxide has been administered to billions of patients for general anesthesia,…
Acute Kidney Injury Acute kidney injury (AKI) is a clinical syndrome that reflects the clinical manifestation of isolated or multiple insults to the kidney. The degree of renal damage ranges…
Introduction Perioperative peripheral nerve injury is a significant source of morbidity for patients, and the second most frequent cause of professional liability for anesthesiologists, accounting for 16% of claims in…
Introduction Numerous preparations of intravenous (IV) fluid are available for the replacement of perioperative fluid losses in patients undergoing major surgery. The selection of a specific fluid may be influenced…
Introduction Acute respiratory distress syndrome (ARDS) is a common phenomenon encountered by anesthesiologists in the operating room and intensive care unit (ICU) setting. It is also a feared complication of…
Introduction/Background The hemostatic system consisting of platelets, procoagulant and anticoagulant, and fibrinolytic and antifibrinolytic activities plays a key role in the maintenance of human viability. It achieves hemostatic balance by…
Introduction Glucocorticoids were introduced into clinical practice in 1949 with the release of a purified preparation known as cortisone. The treatment was revolutionary for patients with primary adrenal insufficiency (AI)…
