The Hindgut
1. About 45% to 75% of ulcerative colitis patients eventually need surgery. Indications are divided into emergency, urgent, and elective. Emergency procedures are done for life-threatening complications of fulminant colitis unresponsive…
Vascular Biology and Vascular Anomalies
1. Development of the vascular system starts in early embryogenesis. • Mesenchymal cells develop into hemangioblasts, some of which become angioblasts. • The formation of de novo vessels is referred to as vasculogenesis;…
The Central Nervous System: Pediatric Neuroanesthesia
1. The Monro–Kellie hypothesis states that the sum of all intracranial contents—brain and interstitial fluid (80%), cerebrospinal fluid (CSF; 10%), blood (10%)—remains constant. 2. Maintenance of cerebral perfusion pressure (CPP) is essential…
Fetal Medicine and Anesthesia for Fetal Surgery
1. Fetal surgery is a rapidly evolving specialty with multiple fetal interventions being performed at different stages of pregnancy. 2. Pregnancy results in various anatomic and physiologic changes that impact anesthetic management….
Abdominal Tumors
1. Liver tumors are rare in children and generally present as a painless mass. 2. Hepatoblastoma is the most common liver tumor in children. 3. Regional analgesia may be contraindicated in patients with…
Risk Management, Assessment and Quality Improvement
1. Anesthesiologists remain in key position to protect and further advance patient safety. 2. Patient safety organizations (PSOs) provide federally protected venue to accumulate patient safety information and make recommendations on a…
Anesthetic Equipment and Facilities
1. Equipment-related adverse events are rare. Even if equipment is faulty, user error or unfamiliarity often plays a part. 2. Critically ill children with very noncompliant lungs require minimal circuit and ventilator…
Anesthesia Outside the Operating Room
1. Because pediatric anesthetics outside the operating room are performed with increasing frequency, it is important for any institution to have a system in place to meet the service needs and…
Endocrine Disease
1. Children with diabetes presenting for surgery should undergo careful preoperative assessment and perioperative planning with an effort to optimize the patient’s condition preoperatively and to minimize the disturbances in glucose…
Hematopoietic System
1. During fetal life, hematopoiesis occurs in several distinct locations, with sequential timing of cellular elements produced during gestation. 2. The primary problem in anemia is impaired oxygen-carrying capacity of the blood…
