Fig. 3.1 Model of emotions’ and attention’s effects on nociception, pain sensation, and pain’s primary and secondary affect. Neural structures likely to have a role in these dimensions are shown…
Fig. 4.1 An organizational framework for understanding the process of third-person pain from signal to outcomes. See text for details The framework begins with the pain signal—observable changes in behavior…
Fig. 8.1 (a–e) Pain-indicative facial movements: shown are those facial movements that are frequently displayed in the context of experimental as well as clinical pain conditions. Facial responses to pain…
Huffman JC, Pollack MH (2003) Predicting panic disorder among patients with chest pain; an analysis of the literature. Psychosomatics 44:222–236CrossRefPubMed Imbierowicz K, Egle UT (2003) Childhood adversities in patients with…
© Springer International Publishing Switzerland 2015Gisèle Pickering and Stephen Gibson (eds.)Pain, Emotion and Cognition10.1007/978-3-319-12033-1_5 5. Neuroplasticity in the Pain, Emotion, and Cognition Nexus Gisèle Pickering1 (1) Clinical Pharmacology Department, University Hospital, CIC Inserm1405 Medical Faculty, Clermont-Ferrand,…
Proteinase-activated receptor (PAR) Activating protease Activating peptide PAR antagonist PAR1 Thrombin TFLLR FR-171113 FXa RWJ-56110 Trypsin RWJ-58259 Granzyme A BMS-200261 APC SCH-79797 Gingipains-R PAR2 Trypsin SLIGKV FSLLRY-NH2 Tryptase SLIGRL GB-83…
Fig. 1 Hyperalgesic priming induces a switch in nociceptor second messenger signaling pathways. In a naïve animal, administration (hindpaw injection) of an inflammatory stimulus (e.g., PGE2) results in transient Gs/PKA-mediated…
Fig. 1 Opioids were applied in the volar forearm of volunteers by dermal microdialysis. Intensity of opioid-induced maximum itch is shown in (a) (visual analog scale 0–10, mean ± SEM). (b) Peak…
Fig. 1 Dimensions of pain 1 Pain-Related Amygdala Circuitry The amygdala is closely interconnected with numerous cortical, subcortical, and brainstem areas. Figure 2 shows key amygdala nuclei and their connections relevant…
Fig. 1 Immunostaining for GABA in a semithin (0.5 μm) section from the L4 segment of a rat that had undergone chronic constriction injury of the left sciatic nerve 2 weeks…
