Fig. 12.1 Schematic representation of the coagulation cascade demonstrating the interplay between coagulation, anticoagulation, clot formation and fibrinolysis. Grey boxes with red text indicate which components of the cascade are…
(1) Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA Abstract The elderly population is growing rapidly, and the prevalence of anemia is…
Fig. 5.1 Forest plot of the odds of mortality for transfusion versus no transfusion from observational studies. Individual references are available on request 5.3 Randomised Controlled Trials on Red Blood…
, Dean Fergusson1 and Lauralyn McIntyre1, 2 (1) Centre for Transfusion Research, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada (2) Department of Medicine (Critical Care), The University of Ottawa,…
Fig. 14.1 Factor concentrations in white-cell-reduced FFP (Taken from Stanworth et al. [2]) 14.1.2 Indications for FFP Use in Critical Illness The use of FFP in critical illness has increased…
TRALI Acute onset within 6 h after a blood transfusion PaO2/FiO2 <300 mmHg Bilateral infiltrative changes on the chest X-ray No sign of hydrostatic pulmonary edema (PAOP <18 mmHg or…
© Springer International Publishing Switzerland 2015Nicole P. Juffermans and Timothy S. Walsh (eds.)Transfusion in the Intensive Care Unit10.1007/978-3-319-08735-1_3 3. Red Blood Cell Transfusion Trigger in Sepsis Jean-Louis Vincent1 (1) Department of Intensive Care, Erasme University Hospital,…
Product class Product Company Technology Status Cross-linked Hb HemAssist (ααHb, DCLHb) Baxter Cross-linked Hb Discontinued; safety; increased mortality US army Cross-linked Hb rHb 1.1 Somatogen Recombinant Hb Discontinued; safety; hypertension…
Fig. 2.1 Schematic diagram demonstrating the possible causes of anemia in critically ill patients 2.2 Anemia of Chronic Disease Anemia of chronic disease (ACD) is a common form of anemia…
© Springer International Publishing Switzerland 2015Nicole P. Juffermans and Timothy S. Walsh (eds.)Transfusion in the Intensive Care Unit10.1007/978-3-319-08735-1_1 1. Introduction Nicole P. Juffermans1, 2 and Timothy S. Walsh3 (1) Department of Intensive Care Medicine, Academic Medical Center, Room G3-206,…
