C Cushing’s disease Definition Cushing’s syndrome results in diverse complex symptoms, signs, and biochemical abnormalities caused by excess glucocorticoid hormone. Pathophysiology The most common cause of Cushing’s syndrome today is…
*Relative to cortisol. Data from Stoelting RK, Hillier SC. Pharmacology and Physiology in Anesthetic Practice. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2006:462. A typical oral replacement dose for Addison’s…
A Acromegaly Definition Growth hormone (GH) hypersecretion, usually caused by a GH-secreting pituitary adenoma (99% of cases), can produce a highly distinctive syndrome in adults called acromegaly. Acromegaly occurs because…
20% normally). LVEDP is often elevated, causing symptoms of pulmonary congestion despite normal LV contractility. LVEDP values that are normal may, in fact, represent a patient who is hypovolemic. Diagnosis…
L Spinal cord injury Definition The spinal cord is vulnerable to trauma, compression by intradural or extradural tumors, and vascular injuries. Incidence and prevalence Approximately 11,000 persons each year sustain…
J Parkinson’s disease Definition Parkinsonism is a clinical syndrome that consists of four cardinal signs: tremor, rigidity, akinesia, and postural disturbances (TRAP). Parkinson’s disease is a common cause of TRAP…
I Neuropathy and myopathy Definition Neuropathy is a general term indicating nerve disorders of any kind. Myopathy is defined as any disorder with structural changes or functional impairment of muscle….
H Multiple sclerosis Definition Multiple sclerosis (MS) is a demyelinating acquired disease of the CNS characterized by random and multiple sites of demyelination of the corticospinal tract neurons in the…
