Anesthesia Key

I Thalassemia Definition Thalassemia is an inherited autosomal recessive disorder resulting in a person’s inability to synthesize structurally normal hemoglobin. Incidence and prevalence Thalassemia major usually affects Greek and Italian…

H Sickle cell disease Definition Sickle cell disease is one of the more commonly inherited hemoglobinopathies. Pathophysiology Sickle cell is a disorder transmitted as an autosomal recessive trait that causes…

G Polycythemia vera Definition and pathophysiology Polycythemia vera is a myeloproliferative neoplastic disorder that generally occurs in patients between 60 and 70 years of age. Hyperactivity of myeloid progenitor cells…

F Leukemia Definition Leukemia is the uncontrolled production of leukocytes caused by cancerous mutation of lymphogenous cells or myelogenous cells. Lymphocytic leukemias begin in lymph nodes or other lymphogenous tissues…

D Hemophilia Definition and incidence Hemophilia is an X-linked recessive disorder. It is a hematologic disorder of unpredictable bleeding patterns. Patients are either deficient in factor IX (hemophilia A) or…

ELISA, Enzyme-linked immunosorbent assay; PF4, platelet factor 4.

C Disseminated intravascular coagulation Definition Disseminated intravascular coagulation (DIC) is a coagulation disorder characterized by ongoing activation of the coagulation cascade in response to a clinical or systemic event. Organ…

B Anemia Definition Anemia is a deficiency of erythrocytes caused by either too rapid a loss or too slow production of the cells. Therefore, numeric concentrations of hemoglobin are reduced,…

F Splenic disorders Definition A palpable spleen is the major physical sign produced by diseases affecting the spleen and suggests enlargement of the organ. The normal spleen is said to…

E Pancreatitis Acute pancreatitis Pathophysiology The cause of pancreatitis is multifactorial. Common causes include alcohol abuse, direct or indirect trauma to the pancreas, ulcerative penetration from adjacent structures (e.g., the…