Appraising Clinical Practice Guidelines
CHAPTER 6 Appraising Clinical Practice Guidelines Jason T. Slyer, DNP, RN, FNP-BC, CHFN, FNAP Primary care providers make clinical decisions on a daily basis. These decisions are often made…
Palliative Care
CHAPTER 5 Palliative Care Eve S. Faber, MD • Jessica Stetz, MD Palliative care is an approach to care that focuses on quality of life for patients and families…
Dementia and Delirium
UNIT X: NEUROLOGIC CONDITIONS CHAPTER 48 Dementia and Delirium Scott J. Saccomano, PhD, GNP-BC, RN Dementia, a syndrome of deterioration of cognition in alert persons that results in their…
Pancreatitis: Acute and Chronic
CHAPTER 24 Pancreatitis: Acute and Chronic Evangelia Davanos, PharmD, BCNSP, CNSC • Ashley Steinberg, MD Pancreatitis, an inflammatory disease of the pancreas, may be classified as acute or chronic….
Valvular Heart Disease
CHAPTER 13 Valvular Heart Disease Kenneth Ong, MD Valvular heart disease affects 2.5% of the population in the United States with an equal gender distribution, but is found more…
Perioperative Supplemental Oxygen to Reduce Perioperative Mortality
Fig. 10.1 The “oxygen cascade” with partial pressure of oxygen (PO 2 ) falling from ambient air to the mitochondria. Factors affecting oxygenation at different levels are shown at the top…
Chlorhexidine Oral Rinse to Reduce Perioperative Mortality
Fig. 12.1 Structure of chlorhexidine (1:6-di[4-chlorophenyldiguanido]-hexane). The two biguanide groups (green arrows) are protonated at physiological pH (as shown in the yellow box) so that the molecule is positively charged Chlorhexidine…
Role of Perioperative Hemodynamic Optimization in Reducing Perioperative Mortality
Authors, Year, Type of study Studies, Number of participants Type of patients Monitoring devices Conclusions Poeze et al. [9], Meta-analysis 30 RCTs, 5,733 pts High-risk surgery, trauma, acute medical sepsis…
Aprotinin: Pharmacological Benefits and Safety Concerns
Meta-analysis Year of publication Number of patients Number of studies OR (CI 95 %) OR (CI 95 %) OR (CI 95 %) – – – – Aprotinin versus tranexamic acid Aprotinin versus aminocaproic…
Consensus Conference on Perioperative Mortality: An Update
Search strategy for meta-analyses of RCTs Systematic [sb.] AND (surgery [tiab] OR surgical* [tiab] OR operation* [tiab]) AND [(myocardial AND infarction) OR (death* OR survival OR mortality OR prognosis)] AND…
