Although adrenergic receptors are thought to be mature at birth, sympathetic innervation is incomplete. After birth, neurotransmitter concentrations increase progressively, reflecting the maturation of sympathetic innervation. When compared to the…
COX-1 is constitutively expressed and catalyzes the production of prostaglandins that are involved in numerous physiologic functions, including maintenance of normal renal function in the kidneys, mucosal protection in the…
A variety of receptors and ion channels have been identified on dorsal root ganglion neurons and on peripheral terminals of nociceptive afferent fibers. These receptors, including purinergic,5 metabotropic glutamatergic, tachykinin,6…
