Pancreatitis
E Pancreatitis Acute pancreatitis Pathophysiology The cause of pancreatitis is multifactorial. Common causes include alcohol abuse, direct or indirect trauma to the pancreas, ulcerative penetration from adjacent structures (e.g., the…
Splenic disorders
F Splenic disorders Definition A palpable spleen is the major physical sign produced by diseases affecting the spleen and suggests enlargement of the organ. The normal spleen is said to…
Inflammatory bowel disease
D Inflammatory bowel disease Definition In the United States, between 200,000 and 300,000 individuals have inflammatory bowel disease, and approximately 30,000 new cases are diagnosed each year. The two major…
Hiatal hernia and gastric reflux
C Hiatal hernia and gastric reflux Definitions Hiatal hernia A hiatal hernia consists of a defect in the diaphragm that allows a portion of the stomach to migrate upward into…
Carcinoid tumors and carcinoid syndrome
A Carcinoid tumors and carcinoid syndrome Definition Carcinoid tumors consist of slow-growing malignancies composed of enterochromaffin cells usually found in the gastrointestinal tract. They may also occur in the lung,…
Gallstones and gallbladder disease
B Gallstones and gallbladder disease Cholecystitis Definition Obstruction of the cystic duct by gallstones results in acute, severe midepigastric pain, typically radiating to the right abdomen. Inspiratory effort usually accentuates…
Hypothyroidism
K Hypothyroidism Definition and incidence Hypothyroidism is a state of thyroid gland hypofunction resulting in decreased circulating concentrations of thyroid hormones. Laboratory findings show decreased plasma T3 and T4 concentrations…
Hyperthyroidism
J Hyperthyroidism Definition Hyperthyroidism is defined as thyroid gland hyperactivity. Thyrotoxicosis is more specifically defined as a state of thyroid hormone excess. The most common cause of thyrotoxicosis in the…
Hyperparathyroidism
H Hyperparathyroidism Definition and incidence Primary hyperparathyroidism is characterized and diagnosed by the presence of elevated serum parathyroid hormone (PTH) levels despite high serum calcium levels. The incidence of primary…