Factors that affect MAC Factors that do not affect MAC Increased MAC Decreased MAC Gender Red hair Elderly patients Duration of anesthesia Hyperthermia Hypothermia Thyroid function Hyponatremia Hypernatremia Hypokalemia/hyperkalemia Chronic…
Chemical Structure 34.1 Ferrous sulfate Chemical Structure 34.2 Zinc sulfate Chemical Structure 34.3 Calcium carbonate References 1. Shils ME, Olson JA, Shike M. Modern nutrition in health and disease. 9th…
Drug class Drug Brand names Dosing option Sulfonylureas Glyburide Regular tablets 1.25–20 mg, 1–2 times/day DiaBeta® Micronized tablets Glynase® PresTab® 1.5–12 mg, 1–2 times /day Glipizide Immediate release Glucotrol® 5–20…
Drug Bolus dose Infusion rate Phenylephrine 100 mcg 1 mcg/kg/min Methoxamine 10 mg NA Norepinephrine 16 mcg 0.1 mcg/kg/min Epinephrine 8 mcg 0.05 mcg/kg/min Metaraminol 5 mg NA Ephedrine 10…
Receptor Location Effect Δ (delta) Brain (pontine nuclei, amygdala, olfactory bulb, deep cortex), peripheral sensory neurons Slight analgesia, physical dependence, antidepressant Κ (kappa) Brain (hypothalamus, periaqueductal gray), spinal cord (substantia…
Drug Common dosing Half-life (h) Time to peak plasma concentration (h) Elimination Short- to intermediate-acting benzodiazepines Alprazolam (Xanax) 0.25–0.5 mg BID–TID for anxiety; maximum 4 mg/day 11.2 (6.3–26.9) 1–2 Renal…
Supplement Typical usage Pharmacology Vitamin A Cataracts Fat-soluble vitamin which supports cell growth and immune function [12] Glaucoma Improving vision Skin conditions B vitamins Fatigue Supports various bodily functions (i.e.,…
14. Richardson JD, Aanonsen L, Hargreaves KM. Antihyperalgesic effects of spinal cannabinoids. Eur J Pharmacol. 1998;345:145–53.PubMed 15. Liu C, Walker JM. Effects of a cannabinoid agonist on spinal nociceptive neurons…
Inhibitors of serotonin reuptake Selective serotonin reuptake inhibitors (SSRIs): fluoxetine, paroxetine, sertraline, citalopram, fluvoxamine Serotonin-norepinephrine reuptake inhibitors (SNRIs): venlafaxine, desvenlafaxine, duloxetine, milnacipran Tricyclic antidepressants (TCAs): amitriptyline, nortriptyline, protriptyline clomipramine, imipramine,…
Drug (date of most recent available labeling) Indication Reason for boxed warning Alternatives Antiemetics Droperidol (Inapsine®) 12/2001 Nausea and vomiting; neuroleptic anesthesia Prolonged QT interval, torsades de pointes Ondansetronb, metoclopramide…
