Histamine Modulators

Sep 18, 2016 by in ANESTHESIA Comments Off on Histamine Modulators

(1) Department of Anesthesiology, Tulane Medical Center, New Orleans, LA, USA (2) Department of Anesthesiology, Louisiana State University, New Orleans, LA, USA     Michael Yarborough Email: myarboro@tulane.edu Introduction Drug Class…

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Pharmacokinetics and Pharmacodynamics of Anesthetics

Sep 18, 2016 by in ANESTHESIA Comments Off on Pharmacokinetics and Pharmacodynamics of Anesthetics

Fig. 1.1 The relationship among the pharmacokinetic processes of absorption, distribution, metabolism, and excretion with the central, peripheral, and site of action compartments Upon closer examination, PK includes even the…

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Antiepileptic Agents

Sep 18, 2016 by in ANESTHESIA Comments Off on Antiepileptic Agents

Chemical Structure 29.1 Gabapentin Chemical Structure 29.2 Phenytoin Chemical Structure 29.3 Carbamazepine Chemical Structure 29.4 Lamotrigine Chemical Structure 29.5 Levetiracetam Chemical Structure 29.6 Topiramate Chemical Structure 29.7 Ethosuximide References 1….

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New Vistas in Neuromuscular Blockers

Sep 18, 2016 by in ANESTHESIA Comments Off on New Vistas in Neuromuscular Blockers

Fig. 52.1 The chemical structures of gantacurium (a) and CW002 (b). The chlorine (a, red circle) substituted at the olefinic double bond of gantacurium was designed to accelerate the inactivation…

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Lipid-Lowering Agents

Sep 18, 2016 by in ANESTHESIA Comments Off on Lipid-Lowering Agents

Fig. 48.1 Acetyl-CoA pathway to its end points Drug Classes Statins Statins are the gold standard for lowering cholesterol. This class of medications was originally created through extraction from a…

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Asthma and COPD Agents

Sep 18, 2016 by in ANESTHESIA Comments Off on Asthma and COPD Agents

Severity Characteristics Therapies Intermittent – mild Daytime symptoms ≤2×/week Short-acting β2 agonist Nocturnal awakenings ≤2×/month Use SABA ≤2×/week FEV1 or PEF ≥80 % predicted Asymptomatic between exacerbations 0 –1 exacerbations/year requiring…

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Central Nervous System Stimulants

Sep 18, 2016 by in ANESTHESIA Comments Off on Central Nervous System Stimulants

Chemical Structure 23.1 Amphetamine (Adderall) Chemical Structure 23.2 Modafinil (Provigil) Chemical Structure 23.3 Armodafinil (Nuvigil) Chemical Structure 23.4 Caffeine Chemical Structure 23.5 Methylphenidate (Ritalin) Chemical Structure 23.6 Atomoxetine (Strattera) HCl…

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Cardiac Surgery

Sep 18, 2016 by in ANESTHESIA Comments Off on Cardiac Surgery

Because the AT-III level recovery varies, thus 20 min after infusion of initial dose, recheck AT-III level and recalculate the additional dose necessary to correct AT-III deficiency. Then it is…

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Chemotherapeutic Agents

Sep 18, 2016 by in ANESTHESIA Comments Off on Chemotherapeutic Agents

Fig. 31.1 Four phases of cell division (Source: Brunton et al. [3]. Copyright © McGraw Hill Companies, Inc) Antimetabolites (S-Phase) Antimetabolite drugs are also referred to as nucleic acid synthesis…

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