INTRODUCTION Print Section Listen One approach to altering the pharmacokinetics of a xenobiotic is to administer a gastrointestinal (GI) evacuant. Selected patients benefit from minimizing systemic exposure by decreasing GI…
INTRODUCTION Print Section Listen Activated charcoal (AC) is an excellent nonspecific adsorbent. Conclusions regarding the role of AC in poison management are achieved through the integration of pharmacologic data, controlled…
INTRODUCTION Print Section Listen Decontamination is a term that describes limiting or minimizing the exposure of a patient to a xenobiotic. This involves removal of a xenobiotic by physical means…
OVERVIEW Print Section Listen For more than 5 decades, medical toxicologists and poison information specialists have used a clinical approach to poisoned or overdosed patients that emphasizes treating the patient…
INTRODUCTION Print Section Listen Most patients with xenobiotic exposures do well with supportive care and close attention to vital physiology. However, one of the fundamental principles of managing an acutely…
CASE STUDY 2 Print Section Listen History A 22-year-old man was brought to the emergency department after being found unconscious at a movie theater. In the field, the paramedics inserted…
CASE STUDY 1 Print Section Listen History Police were called to a public area where a young man was shirtless and acting bizarrely. It was a hot summer day with…
INTRODUCTION Print Section Listen Throughout history, mass poisonings have caused suffering and misfortune. From the ergot epidemics of the Middle Ages to contemporary industrial disasters, these mass events have had…
INTRODUCTION Print Section Listen The term poison first appeared in the English literature around 1225 A.D. to describe a potion or draught that was prepared with deadly ingredients.8,155 The history…
INTRODUCTION Print Section Listen For more than 200 years, American health care providers have attempted to standardize their approach to the assessment of patients. At the New York Hospital in…
