ANESTHESIA

Anesthesia for Bariatric Surgery

Mar 7, 2020 by in ANESTHESIA Comments Off on Anesthesia for Bariatric Surgery

Key Points ▪ In the United States more than two out of three people are overweight or obese. Worldwide, more people are obese than are malnourished. Obesity is becoming the…

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Perioperative Acid-Base Balance

Mar 7, 2020 by in ANESTHESIA Comments Off on Perioperative Acid-Base Balance

Key Points ▪ The presence of a significant acid-base abnormality often signals a sinister underlying problem. ▪ All acid-base abnormalities result from alterations in the dissociation of water. ▪ Only…

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Neuromuscular Monitoring

Mar 7, 2020 by in ANESTHESIA Comments Off on Neuromuscular Monitoring

Key Points ▪ Good evidence-based practice dictates that clinicians always quantitate the extent of neuromuscular block by objective monitoring. ▪ The neuromuscular block should be adjusted to ensure optimal surgical…

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Patient Blood Management: Transfusion Therapy

Mar 7, 2020 by in ANESTHESIA Comments Off on Patient Blood Management: Transfusion Therapy

Key Points ▪ Blood transfusion is safer now than at any other time in history. Advances in donor screening, improved testing, automated data systems, and changes in transfusion medicine practices…

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Basic Principles of Pharmacology

Mar 7, 2020 by in ANESTHESIA Comments Off on Basic Principles of Pharmacology

Key Wordsage, body habitus, clearance, interactions, patient characteristics, pharmacodynamics, pharmacokinetics, volumes of distribution   Key Points ▪ Pharmacokinetics describes the relationship between drug dose and drug concentration in plasma or…

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Management of the Patient with Chronic Pain

Mar 7, 2020 by in ANESTHESIA Comments Off on Management of the Patient with Chronic Pain

Key Points ▪ The normal physiology of neuronal function, receptors, and ion channels is altered by persistent pain. ▪ Because of the large number of sources and manifestation of chronic…

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Opioids

Mar 7, 2020 by in ANESTHESIA Comments Off on Opioids

Key WordsAnalgesia, Biased Agonism, Delta-, Dependence, Hyperalgesia, Kappa- Receptor, Metabolism, Mu-, Pharmacodynamics, Pharmacokinetics, Tolerance   Key Points ▪ Opioids are a vital part of providing the analgesic component of anesthesia…

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Anesthetic Implications of Concurrent Diseases

Mar 7, 2020 by in ANESTHESIA Comments Off on Anesthetic Implications of Concurrent Diseases

Key Points ▪ The history and physical examination most accurately predict the risks of anesthesia and the likelihood of required changes in monitoring or therapy. ▪ For diabetic patients, end-organ…

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Neuromuscular Disorders Including Malignant Hyperthermia and Other Genetic Disorders

Mar 7, 2020 by in ANESTHESIA Comments Off on Neuromuscular Disorders Including Malignant Hyperthermia and Other Genetic Disorders

Key WordsCharcot-Marie-Tooth Disease, Dantrolene, Guillain-Barre Syndrome, Malignant Hyperthermia, Multiple Sclerosis, Muscular Dystrophy, Ryanodine   Key Points ▪ Malignant hyperthermia (MH) is a pharmacogenetic disorder inherited primarily in an autosomal dominant…

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