Screening for Endometrial Cancer
Screening for Endometrial Cancer Annekathryn Goodman More than 95% of the cancers of the uterine corpus are adenocarcinomas arising from the endometrium. In the United States, endometrial cancer is nearly…
Screening for Ovarian Cancer
Screening for Ovarian Cancer Annekathryn Goodman The risk of developing epithelial ovarian cancer (the most common form) is far less than that of developing breast cancer and other gynecologic malignancies;…
Screening for Cervical Cancer
Screening for Cervical Cancer Annekathryn Goodman Almost all cervical cancer is caused by persistent infection with roughly 15 genotypes of human papillomavirus (HPV). The development of new vaccines shown to…
Screening for Breast Cancer
Screening for Breast Cancer Breast cancer ranks as the most common cancer among women, accounting for more than one in four cancer diagnoses, 250,000 new cases, and 40,000 deaths annually…
Glucocorticoid Therapy
Glucocorticoid Therapy David M. Slovik The therapeutic potency of glucocorticoids has led to their widespread use. Although benefits can be substantial, adverse effects are numerous, including serious metabolic derangements and…
Approach to the Patient with Hypothyroidism
Approach to the Patient with Hypothyroidism David M. Slovik Hypothyroidism is a common, readily treatable disorder. Increasingly, patients present with subclinical disease detected either as part of a screening program…
Approach to the Patient with Hyperthyroidism
Approach to the Patient with Hyperthyroidism David M. Slovik Hyperthyroidism is the clinical expression of a heterogeneous group of disorders that produce excess of free thyroxine (T4), triiodothyronine (T3), or…
Approach to the Patient with Diabetes Mellitus
Approach to the Patient with Diabetes Mellitus David M. Slovik Diabetes mellitus is the most prevalent endocrinologic problem encountered in primary care practice. It is a condition of emerging epidemic…
Evaluation of Suspected Diabetes Insipidus
Evaluation of Suspected Diabetes Insipidus David M. Slovik When a patient presents with polyuria and polydipsia, the primary care physician needs to keep in mind the possibility of diabetes insipidus…
Evaluation of Galactorrhea and Hyperprolactinemia
Evaluation of Galactorrhea and Hyperprolactinemia David M. Slovik Discharge of milk or colostrum from the breast in the absence of nursing is referred to as galactorrhea. When it is accompanied…
