Potential New Drugs for Acute and Prophylactic Treatment of Migraines Peter J. Goadsby Nabih M. Ramadan INTRODUCTION Headache is the most common reason for neurologic referral (10), and the majority…
Nonsteroidal Anti-Inflammatory and Miscellaneous Drugs in Migraine Prophylaxis Stefan Evers Ewan J. Mylecharane INTRODUCTION In addition to the recognized drugs of first choice for migraine prophylaxis such as β-adrenoceptor blockers,…
Antiepileptic Drugs in Migraine Prophylaxis Stephen D. Silberstein Peer Tfelt-Hansen Migraine and epilepsy are both chronic, believed to result from brain hyperexcitability, and the therapeutic agents effective for each disorder…
Calcium Antagonists in Migraine Prophylaxis Noboru Toda Peer Tfelt-Hansen Calcium antagonists have been introduced in migraine prophylaxis because of two effects considered to be of potential benefit (3): 1. Their…
Antiserotonin Drugs in Migraine Prophylaxis Peer Tfelt-Hansen Pramod R. Saxena Antiserotonin drugs are the first group of effective agents available for migraine prophylaxis. Originally, these drugs were thought to act…
β-Adrenoceptor Blocking Drugs in Migraine Prophylaxis Peer Tfelt-Hansen Paul Rolan β-Blockers (β-adrenoceptor antagonists) were introduced into medicine for the treatment of angina pectoris and cardiac arrhythmias, but they have subsequently…
Prioritizing Acute Pharmacotherapy of Migraines Peer Tfelt-Hansen Treatment should be prioritized as a joint venture between doctor and patient. The vast majority of migraine attacks are and should be treated…
Antiemetic, Prokinetic, Neuroleptic, and Miscellaneous Drugs in the Acute Treatment of Migraines Peer Tfelt-Hansen William B. Young Stephen D. Silberstein Nausea and vomiting are common symptoms of migraine (48) and…
Triptans, 5-HT1B/1D Receptor Agonists in the Acute Treatment of Migraines Pramod R. Saxena Peer Tfelt-Hansen The triptans belong to a class of compounds known as 5-hydroxytryptamine1B/1D (5-HT1B/1D, previously 5-HT-like/5-HT1D [260])…
Ergot Alkaloids in the Acute Treatment of Migraines Peer Tfelt-Hansen Pramod R. Saxena He gently prevails on his patients to try The magic effects of the ergot of rye. –Lord…
