History of Anesthesia and Introduction to the Specialty
Figure 2.1 “Ether day, 1846” pictured are Gilbert Abbott (the patient), John Collins Warren, M.D. (the surgeon), William T. G. Morton (the anesthetist) and Henry J. Bigelow, M.D. (the junior…
Pharmacology of Local Anesthetics
Fiber type Local anesthetic sensitivity Size Myelination A + Large Yes B ++ Medium Yes C +++ Small No pH: Most local anesthetics are weak bases that exist as an equilibrium…
Pharmacology of Inhalational Anesthetics
Agent Vapor pressure (20 °C) Blood: gas partition coefficienta Fat: blood partition coefficient Metabolism Pungencyb N2O 38,770 mmHg 0.46 2.3 0 None Desflurane 669 mmHg 0.42 27 0.02 % High…
