The Future of Pain Pharmacotherapy
Fig. 19.1 A hypothetical graph of the number of available drugs as a function of time. The scales on the abscissa and ordinate are deliberately not specified (See text for…
PAIN MEDICINE
Opioid Adverse Effects and Opioid-Induced Hypogonadism
Fig. 11.1 Causes of opioid-induced nausea and/or vomiting Since tolerance to opioid-induced nausea and vomiting usually develops within days, prolonged treatment, if any, is usually not needed. Often, decreasing the…
Acute Management of the Opioid-Dependent Patient
A maladaptive pattern of substance use, leading to clinically significant impairment or distress, as manifested by three (or more) of the following, occurring at any time in the 12-month period:…
Pharmacogenomics of Pain Management
Fig. 2.1 Framework of genetic background influencing the response to analgesic drugs The second, more traditional, and better established component of pain related genomics is called pharmacogenomics of pain management…
Sleep Aids
Evidence exists to support that: Chronic insomnia is associated with older age. Benzodiazepines and nonbenzodiazepines are effective in the management of chronic insomnia. However, benzodiazepines, nonbenzodiazepines, and antidepressants pose a…
Monitoring Drug Use and Abuse: The Evolution of a Paradigm
# Factor which may lead to increased medication dosing 1 Progression of the patient’s painful condition 2 Development of a new painful condition 3 Aberrant drug-taking behavior 4 Chemical coping…
Polypharmacy and Drug Interaction
68. Martell BA, Arnsten JH, Ray B, et al. The impact of methadone induction on cardiac conduction in opiate users. Ann Intern Med. 2003;139(2):154–5.PubMedCrossRef 69. Klotz U. Tramadol – the…
Opioids and the Law
© American Academy of Pain Medicine 2015Timothy R. Deer, Michael S. Leong and Vitaly Gordin (eds.)Treatment of Chronic Pain by Medical Approaches10.1007/978-1-4939-1818-8_13 13. Opioids and the Law Selina Read1 and Jill Eckert2, 3 (1) Department of Anesthesiology, Penn…
Topical Analgesics
47. Wallace M, Pappagallo M. Qutenza®: a capsaicin 8% patch for the management of post herpetic neuralgia. Expert Rev Neurother. 2011;11(1):15–27.PubMedCrossRef 48. Simpson DM, Brown S, Tobias J, et al….
The Role of Antidepressants in the Treatment of Chronic Pain
Drug (trade name) Class Available dosages FDA-approved indication Side effects, warningsa,b Notes (trade name) Imipramine TCA 75, 100, 125, or 150 mg Depression Dry mouth, constipation, tremor black, box…
