Genomic and Proteomic Medicine in Critical Care
Chapter 99 Genomic and Proteomic Medicine in Critical Care David Jardine, Mary K. Dahmer, Michael Quasney Pearls • The DNA of two unrelated humans is more than 99.9% identical. •…
CRITICAL CARE
Cardiac Bypass for Repair of Congenital Heart Disease in Infants and Children
Chapter 30 Cardiac Bypass for Repair of Congenital Heart Disease in Infants and Children J. William Gaynor, Darryl H. Berkowitz Pearls • Pediatric patients are not small adults with respect to their…
Bacterial Infection, Antimicrobial Use, and Antibiotic-Resistant Organisms in the Pediatric Intensive Care Unit
Chapter 94 Bacterial Infection, Antimicrobial Use, and Antibiotic-Resistant Organisms in the Pediatric Intensive Care Unit John S. Bradley, Christopher R. Cannavino, Deborah E. Franzon, Susan Duthie Pearls • Delays in…
Central Nervous System Infections Presenting to the Pediatric Intensive Care Unit
Chapter 65 Central Nervous System Infections Presenting to the Pediatric Intensive Care Unit Mark E. Rowin, Erin P. Reade, John C. Christenson Pearls • While the term meningitis implies that…
Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation
Chapter 83 Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation Jennifer A. McArthur, Barbara Bambach, Christine Duncan, Julie-An Talano, Robert T. Tamburro, Jr. Pearls • Patients undergoing allogeneic hematopoietic…
Toxidromes and Their Treatment
Chapter 106 Toxidromes and Their Treatment Ashley N. Webb, Prashant Joshi Pearls • When given for a benzodiazepine overdose, flumazenil may precipitate acute withdrawal in the patient who habitually uses…
The Innate Immune System
Chapter 90 The Innate Immune System Rachel S. Agbeko, Mark J. Peters Pearls • Innate immunity provides the front-line “ready-made” response to pathogen invasion. • These same pathways are activated…
Malignant Hyperthermia
Chapter 124 Malignant Hyperthermia Barbara W. Brandom, Mihaela Visoiu Pearls • Malignant hyperthermia (MH) is a muscle disorder first recognized as a complication of general anesthesia with the potent inhalational…
Neuromuscular Blocking Agents
Chapter 122 Neuromuscular Blocking Agents Joseph D. Tobias Pearls • As neuromuscular blocking agents (NMBAs) result in blockade of skeletal muscle function, these agents cause cessation of ventilatory function, mandating…
Pediatric Renal Replacement Therapy in the Intensive Care Unit
Chapter 72 Pediatric Renal Replacement Therapy in the Intensive Care Unit Jordan M. Symons, Stuart L. Goldstein Pearls • Patients receiving renal replacement therapy require careful monitoring of fluid and…
