Stroke and Intracerebral Hemorrhage
Chapter 63 Stroke and Intracerebral Hemorrhage Stuart Friess, Rebecca Ichord Pearls • Childhood stroke encompasses a wide spectrum of disease that can be categorized into three groups: arterial ischemic stroke,…
CRITICAL CARE
Thrombosis in Pediatric Intensive Care
Chapter 80 Thrombosis in Pediatric Intensive Care John Roy, Paul Monagle Pearls • Vascular access devices are the most common cause of thromboembolic disease in children, and every attempt should…
Status Epilepticus
Chapter 60 Status Epilepticus Cecil D. Hahn, Sam D. Shemie, Elizabeth J. Donner Pearls • Prolonged convulsive and nonconvulsive seizures cause neuronal injury by excitotoxic and hypoxic-ischemic mechanisms related to…
Renal Pharmacology
Chapter 70 Renal Pharmacology Douglas L. Blowey Pearls • For situations when the goal is the maintenance of a serum concentration close to the steady state level throughout the dosing…
Assessment of Cardiovascular Function
Chapter 22 Assessment of Cardiovascular Function Melvin C. Almodovar, Thomas J. Kulik, John R. Charpie Pearls • Cardiovascular assessment and monitoring in the pediatric intensive care unit requires careful integration…
Infectious Syndromes in the Pediatric Intensive Care Unit
Chapter 96 Infectious Syndromes in the Pediatric Intensive Care Unit Sonny Dhanani, Peter N. Cox Pearls • Because of the rapid progression of septicemia from meningococcus and variability of markers…
Molecular Foundations of Cellular Injury: Necrosis, Apoptosis, and Autophagy
Chapter 100 Molecular Foundations of Cellular Injury Necrosis, Apoptosis, and Autophagy Jared T. Muenzer, Craig M. Coopersmith Pearls • As an “accidental” form of death, necrosis is an uncontrolled process….
Endotheliopathy
Chapter 101 Endotheliopathy Yves Ouellette, Jan A. Hazelzet Pearls • Because of their location, endothelial cells have the ability to interact with blood components, such as flow, soluble factors, and…
Hypertension in the Pediatric Intensive Care Unit
Chapter 73 Hypertension in the Pediatric Intensive Care Unit Ronald C. Sanders, Jr., Arno Zaritsky, Karen McNiece-Redwine Pearls • Systemic hypertension, an often underappreciated condition that is increasing at an…
Adverse Drug Reactions and Drug-Drug Interactions
Chapter 118 Adverse Drug Reactions and Drug-drug Interactions Wade W. Benton, Adam W. Brothers, Christa C. Jefferis Kirk, Gretchen A. Linggi Irby, Christopher M. Rubino Pearls • Although adverse drug…
