Screening for Cervical Cancer Annekathryn Goodman Almost all cervical cancer is caused by persistent infection with roughly 15 genotypes of human papillomavirus (HPV). The development of new vaccines shown to…

Screening for Breast Cancer Breast cancer ranks as the most common cancer among women, accounting for more than one in four cancer diagnoses, 250,000 new cases, and 40,000 deaths annually…

Glucocorticoid Therapy David M. Slovik The therapeutic potency of glucocorticoids has led to their widespread use. Although benefits can be substantial, adverse effects are numerous, including serious metabolic derangements and…

Approach to the Patient with Hypothyroidism David M. Slovik Hypothyroidism is a common, readily treatable disorder. Increasingly, patients present with subclinical disease detected either as part of a screening program…

Approach to the Patient with Hyperthyroidism David M. Slovik Hyperthyroidism is the clinical expression of a heterogeneous group of disorders that produce excess of free thyroxine (T4), triiodothyronine (T3), or…

Approach to the Patient with Diabetes Mellitus David M. Slovik Diabetes mellitus is the most prevalent endocrinologic problem encountered in primary care practice. It is a condition of emerging epidemic…

Evaluation of Suspected Diabetes Insipidus David M. Slovik When a patient presents with polyuria and polydipsia, the primary care physician needs to keep in mind the possibility of diabetes insipidus…

Evaluation of Galactorrhea and Hyperprolactinemia David M. Slovik Discharge of milk or colostrum from the breast in the absence of nursing is referred to as galactorrhea. When it is accompanied…

Evaluation of Hirsutism David M. Slovik Hirsutism is the development in women of excessive androgendependent terminal body hair in a male pattern. It is present in 5% to 10% of…