Know Which Weight to Use When Dosing Medications
Know Which Weight to Use When Dosing Medications Edward T. Horn PharmD Volume of distribution (Vd) is a nebulous pharmacokinetic principle that describes the hypothetical volume of plasma into which…
ANESTHESIA
Do Not Use Benzocaine Spray: It Increases the Risk of Methemoglobinemia
Do Not Use Benzocaine Spray: It Increases the Risk of Methemoglobinemia Kelly Grogan MD Topical anesthetics are commonly used for procedures including endotracheal intubation, endoscopy, bronchoscopy, laryngoscopy, orogastric tube placement,…
Have a High Threshold for Administering Vitamin K Intravenously
Have a High Threshold for Administering Vitamin K Intravenously Michael J. Moritz MD Anaphylactoid reactions in patients receiving intravenously (IV) administered vitamin K have been widely reported. A recent review…
Consider the Use of Fluconazole Prophylaxis in Intensive Care Patients with Severe Pancreatitis, Abdominal Sepsis, or Need for Multiple Abdominal Surgeries
Consider the Use of Fluconazole Prophylaxis in Intensive Care Patients with Severe Pancreatitis, Abdominal Sepsis, or Need for Multiple Abdominal Surgeries Lisa Marcucci MD There is a growing awareness of…
Be Alert for Drug-Related Pancreatitis in HIV/AIDS Patients And Consider a Period of Proximal Bowel Rest
Be Alert for Drug-Related Pancreatitis in HIV/AIDS Patients And Consider a Period of Proximal Bowel Rest Lawerence Osei MD Acute pancreatitis is an inflammatory condition of the pancreas, which is…
Check Triglyceride Level in Patients on Propofol Drips
Check Triglyceride Level in Patients on Propofol Drips Amisha Barochia MD Propofol is a lipid-soluble alkylphenol agent that is frequently used to sedate mechanically ventilated patients in the intensive care…
Alkalinize the Urine in Tricyclic Antidepressant Overdose
Alkalinize the Urine in Tricyclic Antidepressant Overdose Eliahu S. Feen MD Jose I. Suarez MD Tricyclic antidepressants (TCAs) are three-ringed organic compounds that have been used for decades in the…
Know the Alternate Routes for Administration of Cardiopulmonary Resuscitation Medications
Know the Alternate Routes for Administration of Cardiopulmonary Resuscitation Medications Eric M. Bershad MD Jose I. Suarez MD In a cardiac arrest, pharmacologic support may be needed to help restore…
Remember that Activated Protein C is not as Useful for Sepsis as Once Hoped
Remember that Activated Protein C is not as Useful for Sepsis as Once Hoped Ronald W. Pauldine MD Activated protein C (APC) exerts a number of biological effects including anti-inflammatory,…
Try to Avoid Using Benzodiazepines for Sleep in the Intensive Care Unit, Especially in the Elderly
Try to Avoid Using Benzodiazepines for Sleep in the Intensive Care Unit, Especially in the Elderly Bryan A. Cotton MD During hospitalization, repeated arousals disrupt sleep continuity. These awakenings are…
