Do not Administer Platelets in Immune Thrombocytopenic Purpura Laith Altaweel MD Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by low platelet count and mucocutaneous bleeding. The estimated incidence…

Have a High Threshold in Transfusing Platelets, Especially in Nonbleeding Patients who are not Preoperative Michael J. Haut MD Platelet transfusion has made a significant contribution to the care of…

Know the Signs of a Transfusion Reaction Eugenie S. Heitmiller MD Signs and Symptoms An acute hemolytic transfusion reaction occurs when immunologic incompatibility between the donor and the recipient results…

Remember that Transfusion-Related Acute Lung Injury is Not Dose Dependent Ala’ S. Haddadin MD Transfusion-related acute lung injury (TRALI) is a syndrome of sudden-onset noncardiogenic pulmonary edema occurring during or…

Consider N-Acetylcysteine or Sodium Bicarbonate Prophylaxis Along with Adequate Hydration to Combat Contrast-Induced Nephropathy Michael J. Moritz MD Contrast-induced nephropathy is the third most common cause of in-hospital acute renal…

Do not Attempt to Convert Oliguric to Nonoliguric Renal Failure with Diuretics Brandon R. Bruns MD Heidi L. Frankel MD Oliguria, recently defined as urine output of less than 0.3…

Aim for 2 Milliliters Per Kilogram Per Hour of Urine Output in Rhabdomyolysis Awori J. Hayanga MD Elliott R. Haut MD Rhabdomyolysis is a syndrome characterized by muscle necrosis and…

Consider Rhabdomyolysis in the Patient who Develops Oliguric Renal Failure after a Prolonged Surgery where Muscle Compression may have Occurred William R. Burns III MD Oliguria, characterized by an hourly…

Be Aware that Lipid-Based Amphotericin Products are Associated with Less Renal Toxicity than Regular Amphotericin but can Still Cause Renal Injury John J. Lewin III PharmD Amphotericin B is a…