Sarcoidosis
76. Sarcoidosis Definition Sarcoidosis is a chronic multisystem inflammatory disease characterized by noncaseating granulomas as well as lymphocytic alveolitis. Incidence In the United States the overall incidence of sarcoidosis ranges…
ANESTHESIA
Pyelonephritis
74. Pyelonephritis Definition Pyelonephritis is a potentially organ-threatening, fatal inflammation of the kidney and renal pelvis secondary to a bacterial infection that begins in the interstitial tissues and rapidly extends…
Scleroderma
77. Scleroderma Definition “Scleroderma” literally means “hard or thickened skin.” The disease is a multisystem disorder characterized by inflammation, tissue fibrosis, and microvascular occlusion as the result of excessive production…
Portal Hypertension
70. Portal Hypertension Definition Portal hypertension is the presence within the portal circulation of a pressure gradient of 12 mm Hg or higher. This malady is associated with numerous conditions…
Polyarteritis Nodosa
69. Polyarteritis Nodosa Definition Polyarteritis nodosa (PAN) is a rare form of systemic necrotizing vasculitis that primarily affects small and medium-sized arteries without glomerulonephritis or vasculitis in the arterioles, capillaries,…
Paget’s Disease of the Bone
67. Paget’s Disease of the Bone Definition Paget’s disease of the bone is a relatively common disease of middle-aged and elderly people in which there is excessive and abnormal bone…
Pemphigoid/Pemphigus
68. Pemphigoid/Pemphigus Definition Pemphoigoid and pemphigus are a group of chronic, autoimmune blistering diseases that are classified depending on the tissue predominately involved. Cicatricial pemphigoid (CP) predominately affects the mucous…
Osler-Weber-Rendu Syndrome
64. Osler-Weber-Rendu Syndrome Definition Osler-Weber-Rendu syndrome (OWRS) is an autosomal dominant, inherited disorder characterized by telangiectases, recurrent epistaxis, and first-degree relative(s) positive for the disorder. Telangiectases are lesions produced by…
Osteogenesis Imperfecta
65. Osteogenesis Imperfecta Definition Osteogenesis imperfecta (OI), one of the most common skeletal dysplasias, is inherited via autosomal dominant mutation(s). It is produced by defective biosynthesis of type I collagen,…
Nephrotic Syndrome
61. Nephrotic Syndrome Definition Nephrotic syndrome is a clinical condition or group of disorders that involves defective kidney glomeruli with massive proteinuria, lipiduria with edema, hypoalbuminemia, and hyperlipidemia. It is…
