Chapter 11 Cognitive Testing for Perioperative Neurocognitive Disorder Lisbeth Evered , BSc, MBiostat, PhD Introduction The term postoperative cognitive dysfunction (POCD) has been used to describe an objectively measurable decline…
Chapter 12 Biomarkers of Postoperative Cognitive Dysfunction: Finding the Signal amid the Noise Miles Berger , MD, PhD, S. Kendall Smith , MD, PhD, and Anver Khan , BA Introduction…
Chapter 10 Comorbidities and Postoperative Neurocognitive Disorder Mervyn Maze , MD and Xiaomei Feng , PhD Introduction Underlying conditions that are associated with persistent inflammation produce conditions likely to result…
Chapter 9 Surgery and the Inflammatory Response Azeem Alam , MBBS, and Daqing Ma , PhD Introduction Surgery has become one of the most important medical interventions available, with 200…
Chapter 8 Pharmacologic (Receptor-Based) Mechanisms of Perioperative Neurocognitive Disorder Lauren G. Powlovich , MD and Zhiyi Zuo , MD, PhD Introduction Perioperative neurocognitive disorder (PND, formerly POCD) is an important…
Chapter 7 Anesthesia and Neurodegeneration Phillip Vlisides , MD and Zhongcong Xie , MD, PhD Introduction Amid growing concern that commonly used anesthetics may induce some degree of neurotoxicity, many…
Chapter 6 Animal Models and Cognitive Testing of Perioperative Neurocognitive Disorders Maryellen F. Eckenhoff , PhD and Colm Cunningham , PhD Introduction Problems of clinical importance often are first noticed…
Chapter 5 Persistent Perioperative Neurocognitive Disorder Does Surgery Accelerate Dementia? Katie J. Schenning , MD and Kirk J. Hogan , MD, JD Introduction The question posed by the title of…
Chapter 4 Postoperative Cognitive Improvement Franchesca Arias , PhD, Kimberly T. Sibille , MA, PhD, and Catherine C. Price , PhD, ABPP-CN Introduction Evidence suggests that increased age, low education,…
Chapter 2 Postoperative Delirium Jennifer Gabbard , MD, Frederick E. Sieber , MD, and Esther S. Oh , MD Introduction The number of adults age 65 and older within the…
