Anesthesia Key

Lower Respiratory Tract Infections

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Lower Respiratory Tract Infections

Lower respiratory tract infections are the most common cause of death globally, representing the leading source of infection among patients admitted to the intensive care unit. Rapid and accurate pathogen…

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Antibiotic Considerations in the Critically Ill

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Antibiotic Considerations in the Critically Ill

Treating infections in critically ill patients is uniquely challenging because of diverse disease states, high rates of antimicrobial resistance, pharmacokinetic changes, and a high risk of mortality that leaves little…

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The Respiratory Triple Pandemic in the Intensive Care Unit

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on The Respiratory Triple Pandemic in the Intensive Care Unit

The anticipated “tripledemic” during the 2023–2024 season—in which simultaneous epidemics of SARS‑CoV‑2, influenza, and respiratory syncytial virus were projected—ultimately fell short of early forecasts. Nevertheless, each virus remains a significant…

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Infection Prevention and Control in the Intensive Care Unit

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Infection Prevention and Control in the Intensive Care Unit

Health care–associated infections are common and burdensome in intensive care units, contributing to increased costs, morbidity, and mortality. The coronavirus disease 2019 (COVID-19) pandemic led to an increase in the…

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Advances and Challenges in Sepsis Care in Low-Resource Settings

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Advances and Challenges in Sepsis Care in Low-Resource Settings

Sepsis is a leading cause of death worldwide, disproportionately affecting low-resource settings. Limited diagnostics, antimicrobial resistance, and scarce critical care capacity compound the burden. Areas for improved care include physiology-based…

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Antibiotic Stewardship for the Intensivist

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Antibiotic Stewardship for the Intensivist

Intensive care units (ICUs) care for the most severely ill patients and consequently account for the largest volume of antibiotic use in the hospital. Critically ill patients must receive optimal,…

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Recognizing and Managing Hemophagocytic Lymphohistiocytosis in Adults in the Intensive Care Unit

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Recognizing and Managing Hemophagocytic Lymphohistiocytosis in Adults in the Intensive Care Unit

Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammatory syndrome increasingly recognized across age groups. This syndrome is driven by pathologic interferon-γ production, which leads to a self-sustaining positive feedback loop resulting in…

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Intensive Care Unit Management of Meningitis and Encephalitis

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Intensive Care Unit Management of Meningitis and Encephalitis

Meningitis and encephalitis are neurologic emergencies that require rapid recognition and treatment. Prompt diagnosis and administration of antimicrobials, alongside adjuvant steroids in select cases, are crucial for treatment and improvement…

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The Global Intensive Care Unit

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on The Global Intensive Care Unit

More than 80% of the world’s population lives in low-income and middle-income countries, yet access to critical care remains limited in these regions. Infectious diseases, especially human immunodeficiency virus, tuberculosis,…

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Optimal Approach to Source Control in Intensive Care Unit Patients

Sep 27, 2026 by Editorial Team in CRITICAL CARE Comments Off on Optimal Approach to Source Control in Intensive Care Unit Patients

Source control is a cornerstone of managing infections and sepsis in the intensive care unit, requiring rapid recognition of infection, targeted diagnostic evaluation, and timely procedural or surgical intervention. This…

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