Inhibition and Facilitation of Nociception
Inhibition and Facilitation of Nociception Jürgen Sandkühler The intensity of pain felt by a patient may not always match the level of nociceptor activation. For example, immediately after an accident…
Anatomy and Physiology of Head Pain
Anatomy and Physiology of Head Pain Karl Messlinger Jonathan O. Dostrovsky Andrew M. Strassman A large body of indirect evidence supports the idea that some types of headaches, including migraine,…
Anatomy of Muscles, Tendons, Joints, Blood Vessels, and Meninges
Anatomy of Muscles, Tendons, Joints, Blood Vessels, and Meninges Lars Edvinsson Marc Abel Vital organs of the body are encased by the skeletal system, either completely or in association with…
Ethical Issues in Headache Research and Management
Ethical Issues in Headache Research and Management Timothy J. Steiner Povl Riis Medical research is the means to a better understanding of the etiologic and pathogenetic mechanisms of human disease….
Principles of Clinical Pharmacology, Randomized Controlled Clinical Trials, and Evidence-Based Medicine in Headache
Principles of Clinical Pharmacology, Randomized Controlled Clinical Trials, and Evidence-Based Medicine in Headache Carl G. H. Dahlöf Paul Rolan Peer Tfelt-Hansen The clinical pharmacology of a drug includes both pharmacokinetics—what…
The History and Examination of Headache Patients
The History and Examination of Headache Patients Jes Olesen David W. Dodick CLINICAL APPROACH TO PATIENT WITH HEADACHE For patients with new-onset or progressive headaches, the approach is similar to…
Societal Burden of the Headache
Societal Burden of the Headache Jenny Berg Nabih M. Ramadan Headache is almost a universal experience in that it affects most people at some stage in their lives. Nevertheless, the…
Impact of the Headache on the Individual and Family
Impact of the Headache on the Individual and Family Carl G. H. Dahlöf Glen D. Solomon Headache is a heterogeneous condition that varies widely with respect to global severity and…
Epidemiology of Headache
Epidemiology of Headache Lars J. Stovner Ann I. Scher Epidemiology has been defined as “the study of distribution and determinants of disease frequency in human populations.” Epidemiologic studies may be…
Classification of Headache
Classification of Headache Jes Olesen Richard B. Lipton Undoubtedly, most physicians consider disease classification to be boring, difficult to learn, and clinically not very useful. In practice, most physicians do…
