Abstract This chapter presents a review of modern pharmacokinetic and pharmacodynamic concepts that comprise the scientific foundation of rational drug selection and administration of intravenous anesthetics. Keywords intravenous anesthetics, pharmacokinetics,…
Abstract Understanding the basic principles of pharmacology is fundamental to the practice of medicine in general, but it is perhaps most relevant to the practice of anesthesiology. It is now…
Abstract Biotransformation is an ancient and vital process that governs a drug’s pharmacokinetics and pharmacodynamics. The enzymes and transporters that control each step in the metabolic pathway are highly polymorphic….
Guidelines for the Use of this List 1 These Web sites have been visited, and information on them may be appropriate for patients, their families, and care providers. 2 Before…
Box App-1-1 Important 1 The list of dosage forms may not be complete and may change over time. 2 Not all drugs and dosage forms are available in each country….
Defining Dignity The term dignity is widely used when discussing and debating various and sometimes contentious issues in end-of-life care. Dying with dignity has powerful and provocative connotations and yet,…
* Also contributing for the Kellogg-Feinberg Economics and Illness Study Group listed at the chapter’s end. ** While carrying out this research, Tapas Kundu has been associated with the Centre…
except the United States, developed countries registered either a decline or no change in population during the last decade, whereas 99% of worldwide population growth took place in developing countries….
The economic domain is not often a priority topic for clinicians; however, economic issues permeate the health care experience of clinicians, patients, and their families and caregivers. For example, reimbursement…
In ancient cultures, physicians did not have central roles in caring for the dying. Physician skills were focused on caring for those for whom a cure was possible. From medieval…
