Receptor Receptor site action α-1 Glycogenolysis, gluconeogenesis, constricts vascular smooth muscle, relaxes GI tract α-2 Constricts vascular smooth muscle, decreases insulin secretion and norepinephrine release β-1 Increases heart rate and…
Figure 2.1 “Ether day, 1846” pictured are Gilbert Abbott (the patient), John Collins Warren, M.D. (the surgeon), William T. G. Morton (the anesthetist) and Henry J. Bigelow, M.D. (the junior…
Fiber type Local anesthetic sensitivity Size Myelination A + Large Yes B ++ Medium Yes C +++ Small No pH: Most local anesthetics are weak bases that exist as an equilibrium…
, John W. Wolfe2 and Jesse M. Ehrenfeld3 (1) Department of Anesthesia, Indiana University School of Medicine, Wishard Memorial Hospital, Indianapolis, IN, USA (2) Department of Anesthesiology, Indiana University Hospital, Indiana University School of…
Figure 1.1 Key milestones on the road to the match (Figure Courtesy J. Ehrenfeld) As with most specialties, applicants must use the ERAS system , whether applying for PGY1 or…
Agent Vapor pressure (20 °C) Blood: gas partition coefficienta Fat: blood partition coefficient Metabolism Pungencyb N2O 38,770 mmHg 0.46 2.3 0 None Desflurane 669 mmHg 0.42 27 0.02 % High…
Physiology of One-Lung Ventilation Raquel R. BartzRichard E. Moon Optimal operating conditions for many cardiothoracic procedures require collapse of one lung, producing a challenge for the anesthesiologist who…
Acute and Chronic Post-Thoracotomy Pain Srinivas PyatiDavid R. LindsayThomas Buchheit Key Points 1. Without adequate analgesia, most patients would experience severe pain following thoracic surgery. 2. Epidural analgesia…
Therapeutic Bronchoscopy, Airway Stents, and Other Closed Thorax Procedures Scott ShoferMomen M. WahidiIan J. Welsby Key Points 1. Therapeutic bronchoscopy is most commonly employed to treat patients with…
Pericardial Window Procedures Hilary P. GrocottHarleena GulatiG. Burkhard Mackensen Key Points 1. Patients presenting for pericardial drainage procedures require a thorough, but often urgent, preoperative evaluation in order…
