© Springer Science+Business Media New York 2015Rifat Latifi, Peter Rhee and Rainer W.G. Gruessner (eds.)Technological Advances in Surgery, Trauma and Critical Care10.1007/978-1-4939-2671-8_7 7. The Lean Innovation Model for Academic Medical Discovery Gabriel Gruionu1 and George C. Velmahos1 (1) Division…
© Springer Science+Business Media New York 2015Rifat Latifi, Peter Rhee and Rainer W.G. Gruessner (eds.)Technological Advances in Surgery, Trauma and Critical Care10.1007/978-1-4939-2671-8_1 1. The New Surgeon: Patient-Centered, Disease-Focused, Technology-Driven, and Team-Oriented Rifat Latifi1 , Stanley J. Dudrick2, 3 and Ronald C. Merrell4 …
© Springer Science+Business Media New York 2015Rifat Latifi, Peter Rhee and Rainer W.G. Gruessner (eds.)Technological Advances in Surgery, Trauma and Critical Care10.1007/978-1-4939-2671-8_2 2. The Ever-Changing Departments of Surgery: The New Paradigm—The Roadmap to a Modern Department…
© Springer Science+Business Media New York 2015Rifat Latifi, Peter Rhee and Rainer W.G. Gruessner (eds.)Technological Advances in Surgery, Trauma and Critical Care10.1007/978-1-4939-2671-8_5 5. Telemedicine for Trauma and Intensive Care: Changing the Paradigm of Telepresence Rifat Latifi1 (1)…
Fig. 7.1 Metaxalone was approved as a muscle relaxant in the 1960s when two small studies suggested benefit in degree of low back spasm over the painful area and decreased…
Fig. 1.1 Schematic displays the defining psychophysical properties that characterize the pain report after an acute high-intensity stimulus (left) and that after a local tissue injury (right). As indicated, in…
Fig. 15.1 In the top row, the three schematics for gas chromatography show that samples containing morphine, hydrocodone, and a combination of the two can be distinguished from one another…
Fig. 10.1 Intracellular opioid actions (With permission from Trescot et al. [5]) Fig. 10.2 Opioid receptors, pre- and postsynaptic (With permission from Trescot et al. [5]) The dopaminergic system in…
Fig. 18.1 Putative mechanism of endocannabinoid-mediated retrograde signaling in the nervous system. Activation of metabotropic glutamate receptors (mGluR) by glutamate triggers the activation of the phospholipase C (PLC)-diacylglycerol lipase (DGL)…
Fig. 14.1 Molecular structure of methadone Methadone’s activity at opioid sub-receptors is unique. Like morphine, methadone has agonist affinity for both the mu and delta opioid receptors. However, in animal…
