!DOCTYPE html PUBLIC “-//W3C//DTD XHTML 1.1//EN” “http://www.w3.org/TR/xhtml11/DTD/xhtml11.dtd”> ANESTHESIA FOR PATIENTS WITH CARDIOVASCULAR DISEASE Endocarditis Prophylaxis • The American College of Cardiology (ACC) and American Heart Association (AHA) currently suggest (class…
• CI = HR × SV/BSA (normal values are 2.5 – 4.2 L/min/m2) where MAP is mean arterial pressure, CVP is central venous pressure, CI is cardiac index, HR is…
Pulse Oximetry: Clinical Considerations In addition to SpO2, pulse oximeters provide an indication of tissue perfusion (pulse amplitude) and measure heart rate. Because SpO2 is normally close to 100%, only…
COX Inhibitors: General Concepts Mechanism of Action: Inhibition of cyclooxygenase (COX), the key step in prostaglandin synthesis. COX-1 receptors are widely distributed throughout the body, including gut and…
!DOCTYPE html PUBLIC “-//W3C//DTD XHTML 1.1//EN” “http://www.w3.org/TR/xhtml11/DTD/xhtml11.dtd”> PREOPERATIVE ASSESSMENT, PREMEDICATION, AND PERIOPERATIVE DOCUMENTATION The preoperative assessment is extremely important and consists of a physical examination and medical history, which includes…
Recommendations from the Society of Ambulatory Anesthesia (SAMBA): 1. Identify patients at risk for PONV. 2. Use management strategies to reduce PONV risk. 3. Use one to two prophylactic…
Atropine Dosage • Premedication (antisialagogue effect): intravenous (IV) or intramuscular (IM) 0.01 to 0.02 mg/kg up to the usual adult dose of 0.4 to 0.6 mg • Severe bradycardia: Larger…
!DOCTYPE html PUBLIC “-//W3C//DTD XHTML 1.1//EN” “http://www.w3.org/TR/xhtml11/DTD/xhtml11.dtd”> NEUROMUSCULAR BLOCKING AGENTS The Basics The neuromuscular junction: Motor neurons and muscle cells are separated by the synaptic cleft. Depolarization of the motor…
Ketamine Mechanism of action: Blocks postsynaptic reflexes in the spinal cord and inhibit excitatory neurotransmitters in selected areas of the brain. Dissociates thalamus from limbic system involved in awareness. NMDA…
