Risk • Rare: 1:125,000,000 • Clusters in Japan and Israel Perioperative Risks • Impaired thermoregulation (risk of fatal hyperpyrexia in infants) • Postop chest infections Perioperative Risks • Impaired thermoregulation…
Risk • Incidence in USA: 3 million. • Annual rates per 1000 new episodes of angina for non-African American men are 28.3 for ages 65–74, 36.3 for ages 75–84, and…
Risk • 1:2000 incidence in Caucasians; rare in non-Caucasians • M:F 10:1; more severe in males • 18-50% incidence in Native Americans Perioperative Risks • Difficult airway and atlantoaxial instability…
Risk • Lifetime prevalence of anaphylaxis is 0.05% to 2%, most common triggers being food, stings, and iatrogenic causes. • Occurs in approximately 1 in 10,000 to 1 in 20,000…
Risk • Estimated incidence of 1-3:100,000. • Mean age of onset is in the 60s, but ALS can occur as early as the 20s. • Disease duration is approximately 3…
Risk • Incidence in USA: 2000 new cases/y. • Per million up to age 9. • Southeast Asia and South Africa have 10-20 times higher incidence. • Within USA, related…
Risk • Prevalence: Estimates ranging from 1.7-3.6%. • Most common cause is vitamin deficiency: 65% vitamin B12; 12% combined folate/vitamin B12; 6% folate. • Pernicious anemia is less common: 1…
Risk • Autoimmune disorders (SLE, RA, scleroderma, cold agglutinin disease). • Lymphoproliferative disorders (CLL, NHL). • Prosthetic heart valves (ball-and-cage, and bileaflet valves). Usually subclinical, but can be severe in…
Risk • One of the most common inherited disorders (1 in 2500 in case of European ancestry; uncommon in Asians) • Less than 10% of individuals with AAT deficiency are…
