APPENDIX C: MANAGEMENT OF MALIGNANT HYPERTHERMIA EMERGENCY THERAPY FOR MALIGNANT HYPERTHERMIA MH Hotline 1-800-644-9737; website: WWW.MHAUS.ORG Outside the US: 1-315-464-7079 DIAGNOSIS VS. ASSOCIATED PROBLEMS Signs of MH • Increasing ETCO2…
APPENDIX B: ANESTHESIA MACHINE CHECKOUT & SETTING UP THE OR ANESTHESIA MACHINE CHECKOUT Checkout only valid for an anesthesia system that conforms to current standards and includes an ascending bellows…
Bronchial Blockers • Bronchial blockers: May require longer to position & more intraop repositioning • Univent tracheal tube (provides CPAP, but cannot ventilate while isolating the lung) • Fogarty catheter…
• Take into account longer duration of action in elderly • Neuromuscular blocking agents • Duration prolonged by ↑ age (if steroid based), mild hypothermia, increased density of block (train-of-four…
Dolasetron (Anzemet): See 5HT3 Antagonists. Droperidol (Inapsine) Indication: (1) Prevention/treatment of postoperative nausea and vomiting. Also used for (2) sedation, GA adjunct, treatment of delirium although alternate drugs are preferred…
(lower should remain OFF until after reperfusion & stabilization) • Foley catheter: Goal urine output >0.5 mL/kg/hr • PRBC in the OR; may also need FFP • Management before clamping…
• In pediatric patients a 20–24 gauge needle may be used for the first cannulation and then exchanged with a larger gauge over a guidewire • Proceed as described in…
• Consider bronchoscopy • Consider bag ventilation • Treat underlying problem BRONCHOSPASM Causes • Preexisting reactive airway disease (asthma) • Manipulation of upper airway (oral endoscopy) • ETT with inadequate…
MAJOR FACTORS AFFECTING UPTAKE Solubility • Partition coefficients express relative solubility of anesthetic gas at equilibrium • Lower partition coefficients imply ↓ solubility, faster equilibration of partial pressure (alveolus ↔…
PHARMACODYNAMICS • Ionization best correlates with onset of action. LAs exist in free equilibrium in both charged (ionized) and neutral (non-ionized) forms: • The ionized form binds to the receptor…
