Local Anesthetics
Local Anesthetics Ayumi Maeda Rebecca D. Minehart I. GENERAL PRINCIPLES A. Chemistry. Local anesthetics are weak bases whose structure consists of an aromatic moiety connected to a substituted amine through…
Anesthesia for Orthopedic Surgery
Anesthesia for Orthopedic Surgery Terese T. Horlocker Denise J. Wedel Key Points Orthopedic surgery is well suited to neuraxial and peripheral regional anesthetic techniques. Improved surgical outcomes have increased their…
Neuromuscular Blockade
Neuromuscular Blockade Bryan Simmons Oleg V. Evgenov The principal pharmacologic effect of neuromuscular-blocking drugs (NMBDs) is to interrupt transmission of synaptic signaling at the neuromuscular junction (NMJ) by interacting with…
Administration of General Anesthesia
Administration of General Anesthesia William J. Sauer Stuart A. Forman The primary goals of general anesthesia are to maintain the health of the patient while safely providing amnesia, hypnosis (lack…
Emergency Preparedness for and Disaster Management of Casualties from Natural Disasters and Chemical, Biologic, Radiologic, Nuclear, and High-Yield Explosive (CBRNE) Events
Emergency Preparedness for and Disaster Management of Casualties from Natural Disasters and Chemical, Biologic, Radiologic, Nuclear, and High-Yield Explosive (CBRNE) Events Michael J. Murray Key Points There are certain principles…
Intravenous and Inhalation Anesthetics
Intravenous and Inhalation Anesthetics Jason S. Lee Ken Solt I. PHARMACOLOGY OF INTRAVENOUS ANESTHETICS Intravenous (IV) anesthetics are commonly used for the induction and maintenance of general anesthesia and for…
Safety in Anesthesia
Safety in Anesthesia Solmaz Poorsattar Manuel May Pian-Smith I. SAFETY IN ANESTHESIA A. Anesthesiology has led the patient safety movement, and anesthesia-related adverse outcomes have drastically declined since the 1960s….
The Anesthesia Machine
The Anesthesia Machine Adeola O. Sadik Gregory Ginsburg I. OVERVIEW The basic function of the anesthesia machine is to prepare a gas mixture of precisely known and variable composition for…
Anesthesia for Otolaryngologic Surgery
Anesthesia for Otolaryngologic Surgery Lynne R. Ferrari Charles Nargozian Key Points The restricted spaces in the airway require an understanding and cooperative relationship between surgeon and anesthesiologist, and the use…
Peripheral Nerve Blockade
Peripheral Nerve Blockade Ban C.H. Tsui Richard W. Rosenquist Key Points Peripheral nerve blocks provide effective anesthesia and analgesia in a site-specific manner with the potential for long-lasting effects. Accurate…
