Nonopioid Analgesic and Adjunct Drugs



Chemical Structure 9.1
Dexamethasone



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Chemical Structure 9.2
Dexmedetomidine


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Chemical Structure 9.3
Acetaminophen/paracetamol


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Chemical Structure 9.4
Ketamine


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Chemical Structure 9.5
Ketorolac


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Chemical Structure 9.6
Celecoxib





References



1.

Cashman JN. The mechanisms of action of NSAIDs in analgesia. Drugs. 1996;52 Suppl 5:13–23. Review.PubMedCrossRef


2.

Jackson LM, Hawkey CJ. COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages? Drugs. 2000;59(6):1207–16. Review.PubMedCrossRef


3.

Viscusi ER, Frenkl TL, Hartrick CT, Rawal N, Kehlet H, Papanicolaou D, et al. Perioperative use of etoricoxib reduces pain and opioid side-effects after total abdominal hysterectomy: a double-blind, randomized, placebo-controlled phase III study. Curr Med Res Opin. 2012;28(8):1323–35.PubMedCrossRef


4.

Bing RJ, Lomnicka M. Why do cyclo-oxygenase-2 inhibitors cause cardiovascular events? J Am Coll Cardiol. 2002;39(3):521–2.PubMedCrossRef


5.

De Oliveira GS, Jr AD, Benzon HT. Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials. Anesth Analg. 2012;114(2):424–33.PubMedCrossRef


6.

Lin J, Zhang L, Yang H. Perioperative administration of selective cyclooxygenase-2 inhibitors for postoperative pain management in patients after total knee arthroplasty. J Arthroplasty. 2013;28(2):207–13.PubMedCrossRef


7.

Sinatra RS, Shen QJ, Halaszynski T, Luther MA, Shaheen Y. Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function. Anesth Analg. 2004;98(1):135–40.PubMedCrossRef


8.

Johnson AG, Seidemann P, Day RO. NSAID-related adverse drug interactions with clinical relevance. An update. Int J Clin Pharmacol Ther. 1994;32(10):509–32.PubMed


9.

Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids – new mechanisms for old drugs. N Engl J Med. 2005;353:1711–23.PubMedCrossRef


10.

Romundstad L, Stubhaug A. Glucocorticoids for acute and persistent postoperative neuropathic pain: what is the evidence? Anesthesiology. 2007;107(3):371–3.PubMedCrossRef


11.

Waldron NH, Jones CA, Gan TJ, Allen TK, Habib AS. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth. 2013;110(2):191–200.PubMedCentralPubMedCrossRef


12.

Tolver MA, Strandfelt P, Bryld EB, Rosenberg J, Bisgaard T. Randomized clinical trial of dexamethasone versus placebo in laparoscopic inguinal hernia repair. Br J Surg. 2012;99(10):1374–80.PubMedCrossRef


13.

Lunn TH, Andersen L, Kristensen BB, Husted H, Gaarn-Larsen L, Bandholm T, et al. Effect of high-dose preoperative methylprednisolone on recovery after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial. Br J Anaesth. 2013;110(1):66–73.PubMedCrossRef

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Sep 18, 2016 | Posted by in ANESTHESIA | Comments Off on Nonopioid Analgesic and Adjunct Drugs
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