Chapter 14 Wound Management
General Principles of Wound Management
• Identify underlying injury to bones, nerves, vessels, ligaments, tendons, muscles, and other structures.
• Decrease the incidence of infection.
The use of nonsterile but clean gloves show no higher infection rate than sterile gloves and cost less.1
Wound care begins with management of the patient, then focuses on the general area of injury, and finally addresses the specific wound. The following principles apply to the management of all wounds, regardless of cause, location, or patient presentation2,3:
• Manage the patient through standard primary and secondary assessments and treatments. Specific wound-related care includes the following:
• According to institutional protocol, perform or assist with the following:
Wound Healing
Wound healing begins immediately after injury. Vasodilatation produces erythema and edema below the epithelial layer that promotes epithelial cell migration within 24 hours of injury. Fibrin is deposited followed by collagen. Epithelialization closes the wound within 48 to 72 hours if skin margins can be approximated and the wound remains uninfected.4
• Compromised vascular supply, such as in diabetes or severe atherosclerosis or smoking
• Medications that slow collagen formation, such as corticosteroids or phenytoin
• Wounds of the lower legs, feet, or toes
• Low tissue oxygen levels, especially in patients with chronic obstructive pulmonary disease, patients with anemia, and those receiving home oxygen therapy
Scarring is the cosmetic perception of wound healing that occurs over weeks or months. The scar is a dynamic process of collagen synthesis and lysis. In balance, this “creative destruction” of scar tissue produces a flat scar. Lack of collagen in genetic conditions can cause keloids and hypertrophic scarring; lack of collagen synthesis occurs from wound ischemia, steroid use, and other factors that reduce scarring yet also reduce skin tensile strength.5
Wound Assessment
• Has the patient declined in function or is a limb threatened with loss from sepsis, infection, or allergy?
• What caused the injury? How did it happen? What were the circumstances surrounding the event?
• When did the injury occur? Where was the patient at the time?
• Where is the wound located? What is the condition of the skin and surrounding tissue?
• What care did the wound receive before the patient arrived at the emergency department (ED)?
• Are motor function, sensation, and perfusion intact distal to the wound?
• Can the wound edges be approximated?
• What is the patient’s general physical condition? Current medications? Medical history?
Additional considerations for existing wounds or ulcers include6–8:
Evaluate all wounds for the presence of foreign bodies:
• Glass and metal objects are identified easily with plain radiographs.
• Matter that has a density similar to that of soft tissue (e.g., wood splinters, thorns, cactus spines, and pieces of plastic) is not found so easily.
• Ultrasound, computed tomography, and magnetic resonance imaging can be used to locate these objects.4
Treatment Considerations
Wound Preparation
Tap water from treated sources of water (such as filtered or disinfected water) is as effective as other solutions to cleanse a wound.9
Contaminated Wounds
Determination of contamination is based on historical evaluation and wound inspection. Establish whether the wounding implement was clean or grossly soiled. Common knife contaminants include meat, poultry, and dirt. A laceration over the knuckle that occurred when the fist struck a human mouth is always considered contaminated. Likewise, a retained foreign body may provide a nucleus of infection. Fungal infections may occur in the presence of retained wood fragments. Wound irrigation, debridement, and foreign body removal are critical for healing to occur without infection.9
Skin Antisepsis and Cleanser
Reducing skin contamination is usually done with chlorhexidine (Hibiclens), a 10% povidone-iodine (Betadine) solution, or hydrogen peroxide. Any benefit may be offset if skin antiseptics spill into the wound because they impair wound defenses, damage delicate tissues, and delay healing. A dilute (1%) povidone-iodine solution is not as toxic to tissue but should be reserved for infection-prone wounds.10
Hair Removal
Wounds in hairy areas heal best without hair in the approximated edges. Unfortunately, shaving abrades the skin, increases wound infection rates, and is cosmetically irritating. Snip hair with scissors or trim it with an electric clipper if removal is necessary. One area that should never be shaved is the eyebrow, as eyebrows provide important landmarks for approximating wound margins and, once shaved, may fail to grow back.11
Mechanical Irrigation
Regardless of the solution or type of irrigation apparatus, place the needle perpendicular to the wound (as close as possible to the surface) and forcefully depress the syringe plunger. Use protective equipment to guard against fluid splatter to the face and eyes and prevent blood-borne pathogen exposure. Splash guards can be attached between the syringe and the catheter to decrease splatter, but they are not a substitute for personal protective equipment.4
Tetanus Immunization
Postexposure immunizations should be given only when needed. Individuals can become sensitized by frequent vaccination, and subsequent injections can cause several days of painful swelling. This type of reaction is the usual source of “tetanus allergy” reported by some patients. Recommendations for tetanus immunization are based on current guidelines from the Centers for Disease Control and Prevention (CDC), which advises that the tetanus vaccine also should contain diphtheria toxin. This combination, dT(Td), is given as a single 0.5-mL intramuscular dose.12
• Tetanus vaccination routinely begins in childhood. Properly vaccinated children receive tetanus, diphtheria, and pertussis vaccines at ages 2, 4, 6, and 18 months, as well as at 4 and 6 years of age. A booster is provided at age 16 years.
• To remain vaccinated, adults should have received the initial tetanus series and be revaccinated a minimum of every 10 years.
• If an adult presents to the ED with a wound that has minimal contamination, assure that they have received both the initial tetanus series as well as revaccination within the past 10 years. If it has been longer than 10 years, they should receive dT(Td) as part of their ED visit.
• If an adult presents to the ED with a wound that is grossly contaminated (tetanus prone), assure that they have received both the initial tetanus series as well as revaccination within the past 5 years. If it has been longer than 5 years, they should receive dT(Td) as part of their ED visit.
• Ideally, for patients whose immunization status is outdated, unclear, or unknown, tetanus prophylaxis should be given as soon after the wound is sustained as possible, although, immunization will be effective if given up to 72 hours after the wound occurred. Immunization may be considered after 72 hours, but there is a risk that tetanus may have become active within the central nervous system at this point and diligent patient follow up should be considered.
• If the patient has not received an initial tetanus series (or has only received one of the series), they should be started on a regimen with 0.5 mL of dT(Td) in the ED. If the patient has a grossly contaminated wound (tetanus prone), simultaneous administration of 250 units of intramuscular antitoxin is recommended.
• Patients with partial immunity, from two or more previous tetanus injections, are considered sufficiently immune. The CDC recommends a booster of 0.5 mL dT(Td), even for patients with grossly contaminated (tetanus prone) wounds.
• Patients over the age of 6 years who have not completed an initial immunization series should be referred to their primary care providers or local health department for a second dT(Td) dose (0.5 mL intramuscularly) in 4 to 6 weeks and a third injection in 6 to 12 months.11,12 New CDC recommendations suggest the first of these doses should be the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine.13
• In 2010, the CDC recommended expanded use of Tdap. A single Tdap dose is recommended for adults aged 19 to 64 years and children aged 11 to 18 years who have completed the recommended childhood DTP/DTaP vaccination series.13
Prophylactic Antibiotics
Antibiotics are not indicated for simple open wounds in healthy patients because the wounds rarely become infected. However, they are indicated for wounds with devitalized tissue, contamination with soil or feces, contact with saliva (bites), or patients with lymphoma. Antibiotics should always be considered an adjunct to debridement and irrigation rather than a substitute.11 The selection of a prophylactic antibiotic depends on many factors, including the location of the wound, the type of pathogens usually encountered with a particular injury, and the fact that most contaminated wounds contain a wide variety of organisms. Little evidence exists to support the routine application of topical antibiotics on simple wounds.4
Anesthesia
Anesthetic Agents
One disadvantage of lidocaine is the pain associated with injection. Warming the solution to 37° C (98.6° F) can minimize this effect. Sodium bicarbonate also reduces the pain associated with lidocaine injection. Buffer lidocaine by adding one part 8.4% sodium bicarbonate (1 mEq/mL) to 10 parts 1% lidocaine (i.e., add 1 mL of sodium bicarbonate to 10 mL of lidocaine). However, this mixture reduces the shelf life of lidocaine from 3 years to a few days, after which the solution will precipitate in the bottle.12
Anesthetic Allergy
Patients frequently report an allergy to lidocaine; however, true allergy to injected anesthetics is uncommon.12 Many reported allergies are actually adverse reactions such as hyperventilation, vasovagal syncope or light-headedness, cardiovascular stimulation from epinephrine, and various idiosyncratic reactions to the injury and subsequent wound repair. Contact dermatitis, caused by topical local anesthetics, also has been reported. This type of reaction is not immunoglobulin E–mediated and poses little risk. If a true allergy is suspected, an anesthetic from a different chemical class can be used. Sterile saline infiltration, guided imagery, and hypnosis are nonpharmacological options. If local anesthesia is not possible, needleless wound closure techniques such as tying hair on the scalp or applying adhesive closure strips (e.g., Steri-Strips) or wound glue should be considered.
Infiltration Anesthesia
• Use the thinnest possible needle, 30 gauge or smaller.
• Minimize the number of skin punctures; a longer needle, inserted to the hub, can cover most of the edge of a wound.
• Perform subsequent needlesticks through already anesthetized skin.
• Inject into the subdermal area rather than into the dermis; raising a wheal is painful.
• Anesthetic agents injected slowly (longer than 10 seconds) are more comfortable than those injected quickly (<2 seconds).